Leonard Herzenberg: The father of modern flow cytometry Leonard Herzenberg was one of the most influential immunologists of his time. Committed to interdisciplinary collaboration and innovation, he would bring together physicists, biologists, and clinicians to tackle some of the most challenging questions in immunology. His pioneering groundwork laid the…

Arguably the most groundbreaking new opportunities for the treatment of disease and injury are Cell and Gene Therapy Products (CGTP) or what the European Medicines Agency (EMA) call Advanced Therapy Medicinal Products (ATMPs). EMA has broken down ATMPs into three main types: At KCAS Bio, we…

KCAS Bio is attending CYTO2024, the 37th annual Congress of the International Society for the Advancement of Cytometry in Edinburgh, Scotland! A great occasion to explore the latest advancements in cytometry science and to discuss our flow cytometry services with the community. At this edition, Alessandra Roberto, PhD…

Dawn Dufield, PhD is the Scientific Officer for Mass Spectrometry and has been with KCAS Bio since 2018. Before joining KCAS Bio, she worked in the quantitative large and small molecule LC-MS/MS field for Pfizer for over 20 years. Dawn has been a pioneer in the Hybrid LCMS field and…

Over the past decade, a continued discussion point has been the idea around analyzing samples on Ligand Binding Assay (LBA) platforms in singlet (one well) versus the standard duplicate analysis (Single sample added to two different wells). In the recent M10 Bioanalytical Method Validation Guideline issued for guidance in June…

At KCAS Bio, we continuously seek ways to improve our processes with sound, logical, scientific, and business-related methods.  One of these areas of evaluation has been sample preparation.  We have improved various segments of bioanalysis (drying for unstable analytes, liquid handling, and plate-based assays for increased efficiency).  We can also…

Pioneers of RNA Medicine: The Collaborative Journey of Katalin Karikó and Drew Weissman In the field of modern medicine, Katalin Karikó and Drew Weissman are recognized for their significant contributions to groundbreaking innovation, specifically within the areas of RNA biology and immunology. Their collaborative efforts paved the way for…

KCAS Bio SAS (Active Biomarkers SAS) based in Lyon France, a full-service bioanalytical and biomarkers solutions provider is very pleased and proud to share that it successfully opened a new Good Laboratory Practice (GLP) Test Facility to provide GLP-grade bioanalytical methods in the context of preclinical studies. Since November 2023,…

In the scientific field, the often neglected fifth sense, the sense of smell, contributes to broadening our understanding of various phenomena, particularly in the field of biomarkers.Here, we will guide you along our lines of thought on the importance of our olfactory sense, and how it contributes to scientific exploration…

For the last decade or so, the outsourcing of crucial research functions by pharmaceutical and biotechnology companies has become increasingly common and has resulted in the rapid growth of the Contract Research Organization (CRO) industry. But the selection of the best CRO partner to work on your critical research programs…

Rosalind Franklin: Unveiling the DNA Helix and Beyond Her name is Rosalind Franklin. Her crucially important X-ray crystallography work was key to the formulation of an accurate description of the double-helical structure of DNA Born on July 25, 1920, in London, England, Franklin emerged as a pioneering figure…

Flow Cytometry has been an invaluable tool for scientific advancement in immunology, oncology, stem cell research, infectious disease, vaccines, and drug development research. As a versatile and powerful technique, it can be used in various ways and tailored to meet your research needs.  Applications include precise evaluation of cell…