PATTERN_AMBER_1320x780_2 Blogs
Read article Understanding AAV Shedding in Tears: KCAS Bio’s Latest Study

Recently, Matthew Pennington, PhD (one of KCAS’s Senior Scientists) was the senior author on a publication entitled “A Validated Droplet Digital Polymerase Chain Reaction Assay for the Detection of Adeno Associated Viral Vectors in Bio Shedding Studies of Tears”. Below, Matt explains the significance in what they accomplished…

KCAS-blog-thumb_2023-08F_Conventional-vs-Spectral Blogs
Read article Spectral vs. Conventional Flow Cytometry

In the rapidly evolving realm of flow cytometry, conventional flow cytometry is gradually being displaced by its advanced counterpart, spectral flow cytometry. These technologies, each with its unique strengths and applications, have revolutionized the way we analyze cells and particles. Let’s dive…

KCAS-blog-thumb_2023-08D_Soluble-Biomarkers Blogs
Read article Soluble Biomarkers: A Global Perspective on Bioanalysis

A biomarker is a defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or biological responses to an exposure or intervention, including therapeutic interventions(1). With the development of innovative and personalized therapies, biomarker tracking is increasingly important to support the clinical development…

PATTERN_AMBER_1320x780_2 Blogs
Read article What Is Immunophenotyping and How KCAS Applies It

Immunophenotyping has undergone a seismic change in less than two decades as panel sizes have increased in complexity from <10 to >40 colors. Let’s explore how immunophenotyping is transforming the field and how FlowMetric, a KCAS…

KCAS-blog-thumb_2023-07D_Flow-Expansion Blogs
Read article KCAS Bio Expands Flow Cytometry Services into Europe

In an exciting development, KCAS, through its subsidiary FlowMetric, is expanding its flow services in Europe. With a history of providing cutting-edge flow services in the EU, KCAS is taking a significant step forward by transitioning services from its Milan, Italy site to…

KCAS-blog-thumb_2023-07B_PK-ADCs Blogs
Read article Recent FDA Guidance for Pharmacokinetics and Antibody Drug Conjugates, and What They Mean for Your Projects at KCAS

With recent guidance released from the FDA, there are changes for PKs (Pharmacokinetics) and ADCs (Antibody Drug Conjugates) that must be clearly understood before making decisions for your drug product testing. ADCs combine the target specificity of monoclonal antibodies with the…

PATTERN_AMBER_1320x780_3 Blogs
Read article Expanding Spectral Flow Capabilities with Cytek Aurora

Spectral flow has come a long way in recent years, transforming from a mere whisper of possibility to an essential tool in bioanalysis. Initially gaining traction in academic institutions, it quickly caught the attention…

KCAS-blog-thumb_2023_Biologics Blogs
Read article Addressing Bioanalytical Challenges in Biologics

Biologics are drugs derived from complex molecules like antibodies. Over the last two decades they have re-emerged as…

Small_Moll Blogs
Read article Cell Sorting in Molecular Biology

As with the lineup of equine subjects above, cell populations can take similar forms and act the same in a lot of ways – but to the trained eye, there are clear…

PATTERN_BLUE_1320x780 Blogs
Read article Overcoming Analytical Challenges in Oligonucleotide

In the world of scientific research and development, certain analytes pose unique challenges that require specialized expertise to overcome. Oligonucleotides, a class of analytes consisting of short DNA or RNA sequences, are notorious for their complexity and demanding nature. With their increasing importance in the…