Therapeutic Area - Respiratory Solutions
Despite the enormous unmet medical need in respiratory medicine, very few new classes of safe and effective therapies have been introduced over the past 40 years. In spite of a clear need, respiratory medicine appears to have fewer new approved therapies than other common disease areas, such as cardiovascular, metabolic and neurological diseases. Because of this, it is difficult to find a reliable CRO that has invested in developing the expertise necessary to successfully conduct many respiratory studies.
KCAS is a trusted and reliable laboratory for your respiratory drug projects
KCAS can help in the current environment by monitoring the status of the immune system both during and after respiratory infection in order to understand the infection/recovery pathway, evaluate relapse factors versus true recovery, and the mechanism of cytokine response. KCAS stands ready to perform flow cytometric immunophenotyping, cytokine profiling in vitro and in vivo, as well as retrospective studies. KCAS has experience with whole blood, fresh, frozen or fixed PBMCs, lymphoid tissue, respiratory samples, serum, and plasma.
KCAS Respiratory Services
The translation of an assay from Discovery to Preclinical/Clinical is an important part of dru…
Methods transferred into a new laboratory need to be re-established for regulatory compliance….
Affinity capture elution (ACE) is a method used in detecting ADA to increase the assay drug to…
The analysis of free amino acids (20 naturally occurring) in plasma or other biological matric…
Bioavailability (BA) is the percentage that a drug or its pro-drug form is absorbed into the g…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
A significant number of drugs contain a chiral center that allows the compound to properly fit…
The accelerated pace within industry for quick “go / no-go” decisions in drug development, nec…
KCAS provides dose form analysis (DFA) for clinical and non-clinical investigations, with a wi…
Hybrid LCMS is a technique which combines an enrichment step (typically an antibody enrichment…
Clinical Sample Kits at KCAS are more than just clinical supplies for the collection of PK sam…
At KCAS, methods are developed with a fit-for-purpose design in mind, based on our Client’s ne…
A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed t…
KCAS has extensive experience in validating methods in a wide range of bioanalytical platforms…
PD Analysis is the assistance with design, regulatory requirements and final data interpretati…
Biomarkers come in many favors. They can vary from serum/plasma analytes to the measurement of…
Pharmacokinetics (PK) is the determination of the extent of Absorption, Distribution, Metaboli…
Tissue bioanalysis is an essential area in understanding the extent of drug distribution, meta…