KCAS provides a truly differentiated approach as one of only a select few CROs offering both large and small molecule development with extensive capabilities and expertise to its clients who are looking for both scientific expertise and excellent customer service. We provide comprehensive GLP / GCP compliant development services from early discovery support through product registration and beyond.
Led by strong, recognized pharmaceutical and biopharmaceutical experts and pioneers in bioanalytical and biomarker services, KCAS has proven success with over 40 years of stable, secure growth.
KCAS Full Service List
Antibody drug conjugates (ADCs) remain a popular oncology therapeutic modality. ADC analyses r…
The translation of an assay from Discovery to Preclinical/Clinical is an important part of dru…
Colorimetric analysis is a method of determining the concentration of a chemical element or ch…
Methods transferred into a new laboratory need to be re-established for regulatory compliance….
Affinity capture elution (ACE) is a method used in detecting ADA to increase the assay drug to…
Aggregate analysis is done to identify potential protein aggregation that can contribute to th…
Alkaline Hematin Kits are not the ordinary run of the mill clinical supply kit. Collecting for…
Since 2006, the KCAS has provided analytical support to companies developing treatments for me…
The analysis of free amino acids (20 naturally occurring) in plasma or other biological matric…
Bioavailability (BA) is the percentage that a drug or its pro-drug form is absorbed into the g…
Cell based neutralization assays encompass a variety of methods that can be utilized in the de…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
A significant number of drugs contain a chiral center that allows the compound to properly fit…
Regulated clinical bioanalysis is a key focus at KCAS. Our data has been used in the approval…
Critical reagents are essential components of analytical methods whose unique characteristics…
Should define what it is first… ie Bridging Validation is a run when one is trying to move fro…
The accelerated pace within industry for quick “go / no-go” decisions in drug development, nec…
KCAS provides dose form analysis (DFA) for clinical and non-clinical investigations, with a wi…
Flow cytometry is a technique used to detect and measure physical and chemical characteristics…
Fluorescence is used mainly for measuring compounds in solution, or in the case of flow cytome…
Hybrid LCMS is a technique which combines an enrichment step (typically an antibody enrichment…
All biotherapeutics will need to undergo immunogenicity assessment sometime in their drug deve…
Clinical Sample Kits at KCAS are more than just clinical supplies for the collection of PK sam…
Luminescence immunoassays use the low-temperature emission of light (as by a chemical or physi…
At KCAS, methods are developed with a fit-for-purpose design in mind, based on our Client’s ne…
A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed t…
KCAS has extensive experience in validating methods in a wide range of bioanalytical platforms…
Multi-plex analysis of biomarkers is a powerful tool for screening of many analytes in a small…
Regulated clinical bioanalysis is a key focus at KCAS, supporting both human and animal health…
Non-clinical (or often referred to as preclinical studies) non GLP samples are often used for…
KCAS’ Kit preparation service can provide kits for sample collection for Pre-Clinical/ Non-Cl…
The discovery phase in drug development requires rapid and reliable data in making key decisio…
PD Analysis is the assistance with design, regulatory requirements and final data interpretati…
Biomarkers come in many favors. They can vary from serum/plasma analytes to the measurement of…
Pharmacokinetics (PK) is the determination of the extent of Absorption, Distribution, Metaboli…
KCAS’ Clinical Sample Kit (CSK) service provides clinical sample kits for all phases of clinic…
Polymeric conjugates are polymer backbones used as delivery systems for drugs conjugated to th…
The extent to which a drug binds to plasma proteins can range from neglible to 99.9+% with com…
The Laboratory Collection Manual provides biological sample collection, processing, storage an…
Biomarkers come in many flavors and can be used as alternatives for assessing the functionalit…
Size Exclusion Chromatography (SEC) is a chromatography method that allows for the separation…
The analysis of a class of lipids referred to as glycosphingolipids (GSL’s). This class of li…
Pharmacological activity of a drug molecule is influenced by many factors. The way a molecule…
Time resolved fluorescence (TRF) relies on the use of very specific fluorescent molecules call…
Tissue bioanalysis is an essential area in understanding the extent of drug distribution, meta…