Two Protein Biomarkers Hybrid LC-MSMS_KCAS Bio 1 Posters & Papers
Read article Method Development and Validation for the Determination of Two Protein Biomarkers by Multiplexed Online and Offline Hybrid LC-MS/MS in Human Heart Tissue

Discover in this poster presented by Taylor Dufield at WRIB 2026 about a fit-for-purpose multiplex LC–MS/MS workflow combining online and offline anti-peptide immunoprecipitation that enables sensitive, selective quantitation of protein biomarkers and binding partners from a single digested tissue sample across multiple species using a validated ICH M10-aligned approach. Overall,…

Biomarker Analog by Hybrid LC-MSMS_KCAS Bio Posters & Papers
Read article Method Development and Validation of a Biomarker Analog by Hybrid LC-MS/MS with Two-Dimensional Chromatography in Human Matrices

Discover in this poster presented by Ryan Darling at WRIB 2026 on how a validated hybrid immunoaffinity LC–MS/MS method using a surrogate peptide and 2D chromatography enables selective, sub-ng/mL quantitation of a KLK1 analog in human plasma, overcoming LBA limitations caused by near-identical endogenous KLK1. If you have any questions…

GlobalHarmonization_KCASBio Posters & Papers
Read article Cross-Site Validation of a 15-Color Spectral Cytometry Panel for Leukocyte Profiling

Discover in this white paper a global collaboration between KCAS Bio and its strategic partner, Crux Biolabs, to harmonize and validate a standardized 15-color spectral flow cytometry panel for pan-leukocyte profiling across multiple sites. If you have any questions about these services or any others offered by…

ADC_ARC Conjugates Presentation AAPS 2025_KCAS Bio Posters & Papers
Read article Bioanalytical Strategies for Therapeutic Drugs and Their Conjugates (ADCs, Oligos, siRNA, ASOs and AOCs/ARCs) by QqQ/HRMS – Strategies and Case Studies

This presentation, given at the 2025 AAPS PharmSci Conference by Dawn Dufield, PhD, Scientific Officer of Mass Spectrometry at KCAS Bio, reviews Bioanalytical Strategies for Therapeutic Drugs and Their Conjugates (ADCs, Oligos, siRNA, ASOs and AOCs/ARCs) by QqQ/HRMS. If you have any questions about these services or any others offered…

Gautam_ICCS_2025 Posters & Papers
Read article Immunophenotypic Characterization of AML Blast Cells: A Pilot Study for Precision Therapeutic Targeting

Discover in this poster presented by Shalini Gautam, PhD, at ICCS 2025, our work on the “Immunophenotypic Characterization of AML Blast Cells: A Pilot Study for Precision Therapeutic Targeting​.“ If you have any questions about these services or others offered by KCAS Bio, please fill out and submit the contact…

Validation Pan-Leukocyte Panel Whole Blood KCAS Bio Posters & Papers
Read article Global Validation of a Pan-Leukocyte Panel with Enumeration for Fresh Whole Blood​

Discover in this poster presented by Heather Evans, PhD, at ICCS 2025, our work on the “Global Validation of a Pan-Leukocyte Panel with Enumeration for Fresh Whole Blood​“. If you have any questions about these services or others offered by KCAS Bio, please fill out and submit the contact us…

Flow-cytometryBasedMultiparametricProfilingOfNeutrophilFunction_KCASBio Posters & Papers
Read article Flow-cytometry based multiparametric profiling of neutrophil function

Discover in this poster presented by Dmitri Negorev at CYTO 2025 on the “Flow-cytometry based multiparametric profiling of neutrophil function”. If you have any questions about these services or any others offered by KCAS Bio, please feel free to contact us using the form below.

Method Development and Validation of a Biomarker Analog by Hybrid LC-MS/MS with Two-Dimensional Chromatography in Human Matrices Posters & Papers
Read article Development of a High Throughput LC-MS/MS 1.5 Plex Assay for Quantitation of Total Antibody (TAb) and Intact Antibody Drug Conjugate (ADC) using Immunoprecipitation by Specific Receptor Capture

Discover in this poster presented by Ryan Darling at the AAPS National Biotechnology Conference 2025 on the use of a hybrid LC-MS/MS approach for the quantitation of total antibody TAb and intact Antibody Drug Conjugate (ADC). If you have any questions about these services or any others offered…

QuantitativeAssayForAnInvestigationalAnti-MalarialMonoclonalantibodyDrugCandidate_KCASBio Posters & Papers
Read article Development and Optimization of a Quantitative Assay for an Investigational Anti-Malarial Monoclonal Antibody Drug Candidate in Human Whole Blood Using Volumetric Absorptive Microsampling (VAMS)

Discover in this poster presented by Jessica Pham at WRIB 2025 on the “Development and Optimization of a Quantitative Assay for an Investigational Anti-Malarial Monoclonal Antibody Drug Candidate in Human Whole Blood Using Volumetric Absorptive Microsampling (VAMS)”. If you have any questions about these services or any others offered by…

CisplatinInHumanPlasmaByLCMSMS__KCASBio Posters & Papers
Read article Determination of Cisplatin in Human Plasma by LC-MS/MS using Hemoglobin to Overcome Matrix Effects

Discover in this poster presented by Bryan Parmentier at WRIB 2025, our work for the sponsor Lilly on the “Determination of Cisplatin in Human Plasma by LC-MS/MS using Hemoglobin to Overcome Matrix Effects“. If you have any questions about these services or any others offered by KCAS Bio, please feel…

SpectralFlowCytometryPanel_KCASBio Posters & Papers
Read article Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational & Clinical Applications

Discover in this poster presented by David Ambrose at WRIB 2025, our work on the Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational and Clinical Applications. If you have any questions about these services or any others offered by…

GENERATION OF BLOOD-DERIVED REFERENCE SAMPLES WITH ENDOGENOUS CYTOKINES-slice Posters & Papers
Read article Generation of Blood-Derived Reference Samples with Endogenous Cytokines

Discover innovative insights into bioanalytical method development with our poster, presented by Christine Bain, Ph.D., at ECCO 2025. This work explores the creation and application of reference samples containing endogenous immune mediators—such as cytokines and chemokines—to effectively evaluate the performance of bioanalytical methods. Download the poster now to learn more…