KCAS-podcast-thumb_TWB-088 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #88: “Reflections on WRIB 2025 in New Orleans – With ALL the Guests!”

In Episode 88 of The Weekly Bioanalysis, hosts Dominic Warrino, Ph.D. and John Perkins, Ph.D present a special WRIB 2025 recap featuring several KCAS Bio scientists who share firsthand insights from their presentations at the major bioanalytical conference. David Ambrose highlights KCAS Bio’s global harmonization of spectral flow cytometry instruments across…

Comparative Overview of Luminex and MSD Platforms For Biomarker Analysis Blogs
Read article Comparative Overview of Luminex and MSD Platforms For Biomarker Analysis

KCAS Bio offers a wide range of biomarker services, from cell-based to soluble biomarker analysis, including ligand binding assays (LBA), across a variety of matrix types.  Soluble biomarker analysis can be achieved on multiple platforms depending on factors such as sample type, required sensitivity, and whether multiplexing is…

Quantitative Flow Cytometry: Applications & Benefits Blogs
Read article Quantitative Flow Cytometry: Applications & Benefits

Quantitative flow cytometry (QFCM) is a specialized technique that enables precise measurement of the absolute number of specific molecules (e.g., receptors, antigens, or intracellular targets) on individual cells or particles. Understanding flow cytometry is essential, as standard methods typically provide qualitative data, where the relative fluorescence intensity is used to…

Highlights From Our AD/PD 2025 Experience Blogs
Read article Highlights From Our AD/PD 2025 Experience

We were happy to participate in the AD/PD™ 2025 International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, held from April 1 to 5, 2025, in Vienna, Austria. The conference was a valuable opportunity to connect with experts, share our experience, and gain insights…

ELISpot Assay: Applications and Challenges Blogs
Read article ELISpot Assay: Applications and Challenges

Initially developed to assess the frequency of circulating antigen-specific Antibody-Secreting Cells (ASC), ELISpot has become a vital tool for quantifying antigen-reactive T-cells by measuring secreted immune mediators such as cytokines or key molecules involved in cell-mediated cytotoxicity. Compared to other assays for monitoring cell-mediated immunity (CMI), such as…

GENERATION OF BLOOD-DERIVED REFERENCE SAMPLES WITH ENDOGENOUS CYTOKINES-slice Posters & Papers
Read article Generation of Blood-Derived Reference Samples with Endogenous Cytokines

Discover innovative insights into bioanalytical method development with our poster, presented by Christine Bain, Ph.D., at ECCO 2025. This work explores the creation and application of reference samples containing endogenous immune mediators—such as cytokines and chemokines—to effectively evaluate the performance of bioanalytical methods. Download the poster now to learn more…

KCAS-podcast-thumb_TWB-087 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #87: “The Evolution of SCIEX’s Partnership with Pharma in Drug Discovery & Development”

In episode 87 of The Weekly Bioanalysis podcast, John Perkins and Dawn Dufield preview the upcoming WRIB conference, where KCAS Bio and Sciex will both have strong representation through scientific presentations, panels, and business development efforts. Special guest, Rahul Baghla of Sciex, discusses the company’s collaboration with KCAS Bio and introduces their…

Comprehensive Bioanalytical Solutions for Inflammatory Bowel Diseases Blogs
Read article Comprehensive Bioanalytical Solutions for Inflammatory Bowel Diseases

When it comes to developing new therapies for inflammatory bowel diseases (IBD), having robust and reliable bioanalytical support is crucial. From the early stages of drug discovery to Phase III clinical trials, our comprehensive bioanalytical solutions are designed to enhance and accelerate your drug development journey in a GCP…

KCAS-podcast-thumb_TWB-086 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #86: “Immunogenicity Discussion w/ Special Guest Cheikh Kane – What is a Lean ADA?”

During episode 86 of KCAS Bio’s “The Weekly Bioanalysis” podcast, our hosts Dom and John are joined by Dr Cheikh Kane, the Vice President of Biopharma Services at KCAS Bio, to discuss immunogenicity. They first define Immunogenicity; what it is and why it is tested, as well as the standard…

KCAS-podcast-thumb_TWB-085 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #85: “Patient-Centric Sampling: Beyond the Clinic and What it Means for Bioanalysis”

Dom and John, the hosts of “The Weekly Bioanalysis”, recently returned from EBF in Barcelona where there was a session on Patient-centric Microsampling, which both of them found fascinating. This inspired both of them to decide it was high time to revisit this part of our industry. In spite of…

KCAS-blog-thumb_2024-12_The Top 4 Challenge2 Blogs
Read article The Top 4 Challenges during Biomarker Assay Development: from Qualification to Validation

Biomarker assay development is pivotal to clinical research and the success of a study, yet the journey from qualification to validation is often complex. In this blog, we discuss four must-know essentials to optimize your assay development process. 1. Understand the Context of Use: Qualification vs. Validation 2. Choosing the…

KCAS-podcast-thumb_TWB-084 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #84: “Small Molecule LC-MS Development and Evolving Approaches to ADC Payloads”

In episode 84 of “The Weekly Bioanalysis”, our special guest, Bryan Parmentier, joins Dom and John to discuss his background and current role at KCAS Bio, offering insights into the field of small molecule method development. He delves into the typical challenges encountered when working with LC-MS analytes, and how…