AusBiotech October 21 - October 23

KCAS Bio will be attending the AusBiotech International Conference 2026, taking place October 21st–23rd at the Gold Coast Convention & Exhibition Centre in Queensland. As Australia’s largest life sciences conference, AusBiotech brings together the life sciences community to connect people, ideas, and opportunities. The conference provides a platform…

Unstable Small Molecule Blogs
Read article Small Molecule Stability in Bioanalysis: Managing Unstable Compounds

Accurate pharmacokinetic data starts with confidence that the concentration measured by LC-MS/MS truly reflects what was present in the biological sample at the time of collection. For some small molecules, maintaining that integrity can be challenging. Structural features such as esters, lactones, aldehydes, and thiols may make a compound…

KCAS-blog-thumb_2023_02-KCAS-ADCs-with-Hybrid News
Read article KCAS Bio’s Ryan Darling to Present at SCIEX Summit 2026

KCAS Bio’s Ryan Darling, Associate Director of Mass Spectrometry Bioanalysis, will present at the SCIEX Summit 2026 on Wednesday, October 7, as part of Day 2 of the virtual event. Advancing Ultrasensitive Bioanalysis for Complex Modalities Ryan’s presentation, “Ultrasensitive multiplexed bioanalysis of complex modalities using the SCIEX 7500+…

KCAS Bio PHX Case Study Image News
Read article KCAS Bio’s Rathna Veeramachaneni, PhD, to Present at the 4th Annual Virtual Phenomenex BioSymposium

KCAS Bio’s Rathna Veeramachaneni, PhD, will join the 4th Annual Virtual Phenomenex BioSymposium on September 15, sharing insights into advanced LC–MS/MS approaches for the bioanalysis of complex antibody conjugates. Advancing Bioanalysis for Complex Antibody Conjugates Rathna’s presentation, “Magnetic Bead-Enabled Hybrid and Enhanced Traditional LC–MS/MS Workflows for the Bioanalysis…

ISSX San Francisco October 11 - October 14

KCAS Bio will be attending the 27th North American Meeting of the International Society for the Study of Xenobiotics (ISSX), taking place October 11-14, 2026, in San Francisco, California. The 2026 meeting, themed “Back to the Future: DMPK Foundations and New Concepts,” will bring together scientists and researchers…

ASH New Orleans December 12 - December 15

The 68th ASH Annual Meeting and Exposition brings together the global hematology community to explore the latest advances in classical and malignant hematology. The meeting features hundreds of scientific and educational sessions covering basic, translational, clinical, and epidemiological research, providing attendees with opportunities to engage with emerging discoveries and…

MAFCA September 17 - September 17

The MAFCA Annual Research Day brings together flow cytometry professionals for a full day of scientific presentations, research updates, and networking. The program features industry experts and multiple discussion tracks focused on the latest advancements, emerging research areas, and innovations in flow cytometry. Connect With Us at MAFCA…

PBSS Del Mar October 1 - October 1

This workshop brings together industry experts and FDA perspectives to examine the key preclinical, bioanalytical, regulatory, and development considerations for successful IND filings for antibody-based therapeutics. Discussions will cover antibodies, antibody-drug conjugates, and multispecific antibodies, with topics ranging from pharmacology, PK/PD, bioanalysis, and toxicology to CMC activities, clinical development…

Flow Cytometry Workflow Blogs
Read article Conventional and Spectral Flow Cytometry: Inside the Modern Analysis Workflow

Choosing between conventional and spectral flow cytometry and understanding exactly how the data travels from instrument to regulated reportable, has become one of the highest-leverage decisions in a biomarker program. The move to spectral flow is the most visible instrument shift of the past decade, but the harder…

Key Trends Animal Health Blogs
Read article Key Trends Shaping Companion Animal Health Studies

The companion animal health industry continues to experience significant growth as pet ownership rises, veterinary medicine advances, and owners increasingly seek innovative treatment options for their animals. Alongside this growth, sponsors developing pharmaceuticals, biologics, diagnostics, and other veterinary health products are navigating a rapidly evolving research environment. As…

LC-MS workflows for ADC Analysis Blogs
Read article Comprehensive LC-MS Workflows for Antibody Drug Conjugate (ADC) Analysis

If an analyte is amenable to analysis, it’s difficult to ignore the benefits that LC-MS/MS can provide. There are numerous chaAntibody-drug conjugates (ADCs) have become one of the fastest growing classes of targeted therapeutics. By combining the specificity of monoclonal antibodies with highly potent cytotoxic payloads, ADCs are designed…

3D Rendering of Antibody Drug Conjugate Molecules – ADC – with cytotoxic payload Posters & Papers
Read article Comprehensive LC-MS Workflows for Antibody Drug Conjugate (ADC) Analysis

This paper, a collaboration between SCIEX and KCAS Bio, presents comprehensive LC-MS workflows for the quantitative analysis of antibody-drug conjugates (ADCs). Using trastuzumab deruxtecan as a model ADC, the study demonstrates sensitive quantification of free payload, total antibody, and conjugated ADC, highlighting the analytical performance and broad dynamic…