Off-The-Shelf Flow Cytometry Panels for Immune Monitoring Blogs
Read article Off-The-Shelf Flow Cytometry Panels for ImmuneMonitoring

At KCAS Bio, we offer expert flow cytometry services designed to support the evolving bioanalytical needs of immunology and biomarker projects for drug development. Whether you’re working in preclinical or clinical settings, our validated off-the-shelf panels save time, reduce risk, and deliver high-quality, reproducible data you can trust. Extensive Portfolio…

KCAS-podcast-thumb_TWB-088 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #88: “Reflections on WRIB 2025 in New Orleans – With ALL the Guests!!”

In Episode 88 of The Weekly Bioanalysis, hosts Dominic Warrino, Ph.D. and John Perkins, Ph.D present a special WRIB 2025 recap featuring several KCAS Bio scientists who share firsthand insights from their presentations at the major bioanalytical conference. David Ambrose highlights KCAS Bio’s global harmonization of spectral flow cytometry instruments across…

Comparative Overview of Luminex and MSD Platforms For Biomarker Analysis Blogs
Read article Comparative Overview of Luminex and MSD Platforms For Biomarker Analysis

KCAS Bio offers a wide range of biomarker services, from cell-based to soluble biomarker analysis, including ligand binding assays (LBA), across a variety of matrix types.  Soluble biomarker analysis can be achieved on multiple platforms depending on factors such as sample type, required sensitivity, and whether multiplexing is…

KCAS-podcast-thumb_TCF-019 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #19: “Building on Backbone Panels: Standardization, Speed, and Integration”

In the 19th episode of “The Conversational Flow”, our hosts, Brian and Adam, dive into the utility and innovation behind backbone panels in spectral flow cytometry, spotlighting a recent paper from BMS that presents a robust, flexible assay designed for immune monitoring using the Aurora platform. They discuss how backbone…

QuantitativeAssayForAnInvestigationalAnti-MalarialMonoclonalantibodyDrugCandidate_KCASBio Posters & Papers
Read article Development and Optimization of a Quantitative Assay for an Investigational Anti-Malarial Monoclonal Antibody Drug Candidate in Human Whole Blood Using Volumetric Absorptive Microsampling (VAMS)

Discover in this poster presented by Jessica Phan at WRIB 2025 on the “Development and Optimization of a Quantitative Assay for an Investigational Anti-Malarial Monoclonal Antibody Drug Candidate in Human Whole Blood Using Volumetric Absorptive Microsampling (VAMS)”. Quantitative Assay for an Investigational Anti-Malarial Monoclonal Antibody Drug Candidate |…

CisplatinInHumanPlasmaByLCMSMS__KCASBio Posters & Papers
Read article Determination of Cisplatin in Human Plasma by LC-MS/MS using Hemoglobin to Overcome Matrix Effects

Discover in this poster presented by Bryan Parmentier at WRIB 2025, our work for the sponsor Lilly on the “Determination of Cisplatin in Human Plasma by LC-MS/MS using Hemoglobin to Overcome Matrix Effects“. Cisplatin In Human Plasma By LC-MS/MS | KCAS BioDownload If…

SpectralFlowCytometryPanel_KCASBio Posters & Papers
Read article Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational & Clinical Applications

Discover in this poster presented by David Ambrose at WRIB 2025, our work on the Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational and Clinical Applications. Spectral Flow Cytometry Panel | KCAS Bio…

Quantitative Flow Cytometry: Applications & Benefits Blogs
Read article Quantitative Flow Cytometry: Applications & Benefits

Quantitative flow cytometry (QFCM) is a specialized technique that enables precise measurement of the absolute number of specific molecules (e.g., receptors, antigens, or intracellular targets) on individual cells or particles. Understanding flow cytometry is essential, as standard methods typically provide qualitative data, where the relative fluorescence intensity is used to…

Highlights From Our AD/PD 2025 Experience Blogs
Read article Highlights From Our AD/PD 2025 Experience

We were happy to participate in the AD/PD™ 2025 International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, held from April 1 to 5, 2025, in Vienna, Austria. The conference was a valuable opportunity to connect with experts, share our experience, and gain insights…

ELISpot Assay: Applications and Challenges Blogs
Read article ELISpot Assay: Applications and Challenges

Initially developed to assess the frequency of circulating antigen-specific Antibody-Secreting Cells (ASC), ELISpot has become a vital tool for quantifying antigen-reactive T-cells by measuring secreted immune mediators such as cytokines or key molecules involved in cell-mediated cytotoxicity. Compared to other assays for monitoring cell-mediated immunity (CMI), such as…

Frequently Asked Questions About KCAS Bio’s Dose Formulation Analysis Blogs
Read article Top Frequently Asked Questions About KCAS Bio’s Dose Formulation Analysis Services

Dose Formulation Analysis (DFA) is a critical component in regulated nonclinical studies, ensuring accurate dosing and supporting toxicokinetic assessments. At KCAS Bio, we specialize in providing comprehensive DFA services. Below are the top frequently asked questions about Dose Formulation Analysis and our services: 1. What is Dose Formulation Analysis, and…

GENERATION OF BLOOD-DERIVED REFERENCE SAMPLES WITH ENDOGENOUS CYTOKINES-slice Posters & Papers
Read article Generation of Blood-Derived Reference Samples with Endogenous Cytokines

Discover innovative insights into bioanalytical method development with our poster, presented by Christine Bain, Ph.D., at ECCO 2025. This work explores the creation and application of reference samples containing endogenous immune mediators—such as cytokines and chemokines—to effectively evaluate the performance of bioanalytical methods. Download the poster now to learn more…