Blogs
Cell-based immunotherapies like Chimeric Antigen Receptor (CAR)-T cell therapy have been transforming the treatment of hematologic malignancies for more than a decade. Several groundbreaking studies (1) have led to a growing interest in applying these cell-based therapies to other T and B cell-mediated diseases. One emerging application of CARs is…
Podcasts
Episode 17 of The Conversational Flow podcast, hosted by Brian Wile and Adam Cotty, dives into the evolving landscape of flow cytometry networking and regulatory guidance, where they analyze recent FDA biomarker validation guidance, comparing it to existing industry standards like CLSI H62. Our hosts explore the challenges of harmonizing flow cytometry…
Podcasts
In episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology…
Podcasts
In this exciting 15th episode of The Conversational Flow podcast, titled “Fantastic Fluorophores and Where to Find Them,” hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as…
Posters & Papers
This infographic explores the key trends in flow cytometry, software and instrumentation based on results from a recent Spotlight survey. It highlights the top challenges for biomarker analysis using flow cytometry, including lack of standardized control materials, sourcing a suitable laboratory and uncertain regulatory expectation, as well as what the…
Posters & Papers
Please download this poster, “Validation of a 15-Color Spectral Flow Cytometry Panel for Globally Harmonized Comprehensive Leukocyte Profiling in Human Whole Blood: Translational and Clinical Applications “ CYTEK_ValidatedPanels_EBF2024_20241118Download…
Podcasts
A flow cytometry backbone panel is a set of antibodies that can be used as a starting point for identifying cell types, and then supplemented with additional markers. On the most recent episode of “The Conversational Flow”, our hosts, Brian and Adam, spend some time together as they answer the questions…
Podcasts
During the most recent episode of “The Conversational Flow” podcast, our hosts Brian and Adam talk about those times when a smaller panel might be desirable over a larger panel. To dive deep into this discussion and really analyze all the angles of these questions, the guys have invited a…
Blogs
We are thrilled to announce a major milestone in the evolution of our global clinical support services. After months of detailed planning, collaboration, and execution, we’ve successfully integrated spectral flow cytometry at our KCAS Bio sites in Philadelphia, PA, USA; Lyon, France; and Crux Biolabs, our…
Podcasts
In the 12th episode of “The Conversational Flow” podcast, Brian and Adam welcome two special guests – Sean Burke of Denovo Software and Ryan Brinkman of Dotmatics – who join them to discuss the answers to a number of specific questions about High Content Analysis: How can we manage and…
Podcasts
During this special episode of “The Conversational Flow” our hosts, Brian and Adam, welcome two guests: John Bucksath, CEO of KCAS Bio, and Stefan Cross, CEO of Crux Biolabs. These two guests discuss the elements and advantages of their organizations’ new partnership between KCAS’ US and European locations and Crux’s…
Blogs
Spectral flow cytometry and the growing array of commercially available fluorophores have led to the development of increasingly complex immunophenotyping panels. Generating robust data depends not only on a strong panel design but also on the use of appropriate reference controls and a solid understanding of spectral unmixing principles. …