webinars
In drug development, there is a growing demand for ultrasensitive bioanalytical platforms and kits, especially in disciplines like neuroscience, where analytes are often present at very low concentrations in peripheral circulation. KCAS Bio addresses this demand by offering a spectrum of technologies, from dedicated platforms to ultra-sensitive kits on conventional…
webinars
In the evolving landscape of drug development, biomarkers are increasingly vital in driving decisions across preclinical and clinical studies. From patient stratification and efficacy monitoring to safety assessments and pharmacodynamic evaluations, biomarkers are critical tools for reducing development timelines and increasing the likelihood of regulatory success. But with so many…
Blogs
In a bioanalytical CRO, method development is a critical step to ensure reliable and meaningful data that meets the client’s requirements. At our KCAS Bio – Lyon site, our method development team specializes in designing and optimizing ligand-binding assay (LBA) methods tailored to our clients’ specific objectives. While…
Blogs
In the process of drug discovery, an IC₅₀ assay serves as a pivotal component in the development of cutting-edge therapeutics. An effective assay can quantify the potency of compounds, enable side-by-side comparisons with competing compounds, and track how a compound performs over time. Quantifying compound inhibition also assists with pre-clinical…
webinars
Webinar Description: Biomarkers are a critical aspect of bioanalytical testing, as they provide a vast amount of information, from the effects of a drug on the subject to determining the drug’s mechanism of action and the correct dose for a patient. When developing a biomarker, it is important to understand…
Blogs
In the ever-evolving landscape of pharmaceutical research, biodistribution studies play a pivotal role in understanding how drugs and therapies are distributed within the body. These studies are critical for assessing the efficacy and safety of new treatments, particularly in the realm of cell…
Blogs
Recently, Matthew Pennington, PhD (one of KCAS’s Senior Scientists) was the senior author on a publication entitled “A Validated Droplet Digital Polymerase Chain Reaction Assay for the Detection of Adeno Associated Viral Vectors in Bio Shedding Studies of Tears”. Below, Matt explains the significance in what they accomplished…
Blogs
Immunophenotyping has undergone a seismic change in less than two decades as panel sizes have increased in complexity from <10 to >40 colors. Let’s explore how immunophenotyping is transforming the field and how KCAS Bio is at the forefront of this…
Blogs
In an exciting development, KCAS, through its subsidiary FlowMetric, is expanding its flow services in Europe. With a history of providing cutting-edge flow services in the EU, KCAS is taking a significant step forward by transitioning services from its Milan, Italy site to…
Blogs
With recent guidance released from the FDA, there are changes for PKs (Pharmacokinetics) and ADCs (Antibody Drug Conjugates) that must be clearly understood before making decisions for your drug product testing. ADCs combine the target specificity of monoclonal antibodies with the…
Blogs
Spectral flow has come a long way in recent years, transforming from a mere whisper of possibility to an essential tool in bioanalysis. Initially gaining traction in academic institutions, it quickly caught the attention…
Blogs
Biologics are drugs derived from complex molecules like antibodies. Over the last two decades they have re-emerged as…