In Episode #33 of The Conversational Flow, hosts Adam and Brian explore the latest developments in flow cytometry, immunology, and the evolving CRO industry. They examine new research into T-cell dynamics in graft-versus-host disease and regulatory T-cell stability, highlighting how flow cytometry and complementary technologies are advancing our understanding…
Blogs
Here is a scenario we encounter regularly. A sponsor has a promising biologic, a T cell-engaging bispecific, a Treg-depleting antibody, or a checkpoint inhibitor with a novel target. The tox species are cynomolgus macaque, minipig, or dog. And the clinical team wants to know: what will we actually see…
Episode #32 of The Conversational Flow explores several significant developments shaping the flow cytometry and biopharmaceutical industries, including advances in antibody drug conjugates (ADCs), questions surrounding circadian timing in cancer treatment, and major life sciences acquisitions. Our hosts, Brian and Adam, discuss how improvements in ADC linker technology and…
Episode 31 of The Conversational Flow Podcast dives deep into some of the most exciting developments currently shaping the future of cell therapy, flow cytometry, and AI-driven drug development. Our hosts, Brian and Adam, discuss major advances in allogeneic and in vivo CAR-T therapies, including how new manufacturing platforms…
The main discussion of this 30th episode of “The Conversational Flow” centers on automation in flow cytometry, focusing on a recent paper comparing three major sample preparation systems and their impact on efficiency, standardization, and error reduction. Our hosts, Adam and Brian, explore how automation can significantly reduce hands-on…
In episode #29 of “The Conversational Flow” podcast, our hosts, Brian and Adam, are joined by guests from Accelerating Cancer Immunotherapy Research (ACIR), a nonprofit dedicated to sharing important advances in cancer immunotherapy with the scientific community and the public. Ute Burkhardt discusses her background in cancer vaccines and…
In episode 28 of “The Conversational Flow”, our hosts, Adam and Brian, discuss why standardization is essential for credible flow cytometry data at scale. They walk through the biggest sources of variability – reagents and lots, sample handling and shipping time, anticoagulants and processing choices (whole blood vs. PBMCs,…
Posters & Papers
Please download this poster, “Flow Cytometric Analysis of Urine Cell 18-Color Immunophenotyping Panel.”
Blogs
Immunophenotyping has undergone a seismic change in less than two decades as panel sizes have increased in complexity from <10 to >40 colors. Let’s explore how immunophenotyping is transforming the field and how KCAS Bio is at the forefront of this…
Biologics are drugs derived from complex molecules like antibodies. Over the last two decades they have re-emerged…
Due to its ability to analyze multiple parameters across different cell types within a sample, flow cytometry provides rich and clinically valuable data sets from even small volumes of blood. However, flow cytometry is a challenging platform to master, and requires significant investment in equipment and technical training.