KCAS-podcast-thumb_TWB-088 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #88: “Reflections on WRIB 2025 in New Orleans – With ALL the Guests!!”

In Episode 88 of The Weekly Bioanalysis, hosts Dominic Warrino, Ph.D. and John Perkins, Ph.D present a special WRIB 2025 recap featuring several KCAS Bio scientists who share firsthand insights from their presentations at the major bioanalytical conference. David Ambrose highlights KCAS Bio’s global harmonization of spectral flow cytometry instruments across…

ELISpot Assay: Applications and Challenges Blogs
Read article ELISpot Assay: Applications and Challenges

Initially developed to assess the frequency of circulating antigen-specific Antibody-Secreting Cells (ASC), ELISpot has become a vital tool for quantifying antigen-reactive T-cells by measuring secreted immune mediators such as cytokines or key molecules involved in cell-mediated cytotoxicity. Compared to other assays for monitoring cell-mediated immunity (CMI), such as…

KCAS-podcast-thumb_TWB-087 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #87: “The Evolution of SCIEX’s Partnership with Pharma in Drug Discovery & Development”

In episode 87 of The Weekly Bioanalysis podcast, John Perkins and Dawn Dufield preview the upcoming WRIB conference, where KCAS Bio and Sciex will both have strong representation through scientific presentations, panels, and business development efforts. Special guest, Rahul Baghla of Sciex, discusses the company’s collaboration with KCAS Bio and introduces their…

Cutting-Edge PK and Immunogenicity Strategies for Next-Generation ADCs, ARCs, and Conjugated Biotherapeutics Webinars
View webinar Cutting-Edge PK and Immunogenicity Strategies for Next-Generation ADCs, ARCs, and Conjugated Biotherapeutics

As the field of biotherapeutics rapidly evolves, the development of advanced conjugated therapies such as Antibody-Drug Conjugates (ADCs), Antibody-RNA Conjugates (ARCs), siRNA/oligos, and antibody-peptide conjugates has gained significant momentum. These next-generation therapeutics offer promising efficacy and safety profiles for treating various conditions, including cancer, rare diseases, and in vaccine development.

Neutralizing Antibody Assay Development Blogs
Read article Neutralizing Antibody Assay Development

What Are Neutralizing Antibody (NAb) Assays? Neutralizing antibodies (NAbs) are a subset of anti-drug antibodies (ADAs) that play an important role in evaluating the immunogenicity, safety, and efficacy of a drug product. While most drugs carry a low risk of eliciting NAbs and do not require a validated NAb…

The Science and Beyond at EIP Lisbon Blogs
Read article The Science and Beyond at EIP Lisbon

Last month, Elodie, Magali, and I found ourselves in Lisbon—not for a spring getaway (though the weather was a delightful preview of the season) and certainly not for ultra-trail training (although the city’s hills did give our calves a solid workout!). Instead, we were there for EIP, an event…

KCAS-podcast-thumb_TWB-086 Podcasts
Listen to podcast Podcast (The Weekly Bioanalysis) Eps #86: “Immunogenicity Discussion w/ Special Guest Cheikh Kane – What is a Lean ADA?”

During episode 86 of KCAS Bio’s “The Weekly Bioanalysis” podcast, our hosts Dom and John are joined by Dr Cheikh Kane, the Vice President of Biopharma Services at KCAS Bio, to discuss immunogenicity. They first define Immunogenicity; what it is and why it is tested, as well as the standard…

KCAS-blog-thumb_2024-011_ADA_Immunogenicity Assay Development Blogs
Read article The Critical Role of Immunogenicity in Drug Development: Why It Matters

Immunogenicity, why do we keep talking about it? Immunogenicity can, in the simplest of terms, be described as a subject’s ability to generate antibodies specific to the dosed protein therapeutic. While stating it this way understates the complexity of the immune system and the methods needed to detect and characterize…

KCAS-blog-thumb_2024-09_USevents1 Blogs
Read article KCAS Bio’s Autumn 2024 Conferences

KCAS Bio is excited to announce our participation in several premier conferences throughout the United States this fall. These events bring together experts, innovators, and leaders in pharmaceuticals, biotechnology, and clinical research to exchange insights, explore the latest technologies, and drive the future of scientific discovery. As a trusted provider…

KCAS-event_2024-03_EIP April 22 - April 24

The European Immunogenicity Platform (EIP) is a central meeting place for scientists and biopharmaceutical companies in Europe. The goal of the EIP is to improve knowledge and expertise in immunogenicity. This is achieved through collaboration between scientists and industry experts. The EIP works with companies, institutes, and professionals involved in…