KCAS-blog-thumb_2023_Biologics Blogs
Read article Addressing Bioanalytical Challenges in Biologics

Biologics are drugs derived from complex molecules like antibodies. Over the last two decades they have re-emerged as…

PATTERN_BLUE_1320x780_2 Blogs
Read article FlowMetric and Cytek Partner on Flow Cytometry

Business Wire – May 24, 2023 11:00 AM EST – In an effort to continue providing the…

KCAS-blog-thumb_2023_Navigating-Growth Blogs
Read article KCAS Growth: Navigating Company Expansion with Integrity and Engagement

Clinical research carries significant risks and numerous obstacles that must be overcome to achieve success. Identifying the ideal Contract…

KCAS-blog-thumb_2023_kcas-flow-for-cgt Blogs
Read article Molecular Bioanalysis for Cell and Gene Therapies

Being that it is a relatively “niche” segment of the industry, there are several key areas that need to be considered in the field of molecular services related to cell and gene therapies. First and foremost, it is important to recognize that regulatory guidelines within this field are…

PATTERN_AMBER_1320x780_2 Blogs
Read article Guiding the Way: Creating a Roadmap for Your Functional Assays

Understanding the interactions between drugs and biological systems is critical for the success of a new drug. One key tool in this process is functional assays. Functional assays are customized assays that evaluate the impact of drugs on the functionality of cells. They test for a drug’s specific biological mechanism…

KCAS-blog-thumb_2022_GLP-CGT Blogs
Read article The Role of GLP Toxicology Studies in Bioanalysis for CGT

Cell and Gene Therapies (CGTs) has an estimated market size value in 2022 of USD 8.22 billion and a revenue forecast in 2030 of USD 24.5 billion. This is a CAGR (compound annual growth rate) of 14.6% from 2022 to 2030. Needless to say, the…

KCAS-blog-thumb_2022_immunophenotyping-1 Blogs
Read article Flow Cytometry Services: Immunophenotyping

Due to its ability to analyze multiple parameters across different cell types within a sample, flow cytometry provides rich and clinically valuable data sets from even small volumes of blood. However, flow cytometry is a challenging platform to master, and requires significant investment in equipment and technical training.

KCAS-blog-thumb_2022_Molecular-CGT Blogs
Read article Cell and Gene Therapy Bioanalytical Solutions

With the extensive advances in technologies like CRISPR and CAR-T, cell and gene therapy has grown to become a viable way for treating Cancer as well as other diseases. Our team has over 100+ years of collective expertise in molecular services using qPCR and ddPCR for support of…

KCAS-blog-thumb_2022_Webinar-CGT-June-2022-1 Webinars
View webinar Upcoming KCAS Webinar (June 24th): “The Age of Cell and Gene Therapies is Upon Us – So What Does That Mean for Bioanalysis?”

Being produced by Xtalks on Friday, June 24, 2022 | 12pm EDT (NA) / 5pm BST (UK) / 6pm CEST (EU-Central) 60 min Webinar Description: Cell and gene therapies (CGTs) are types of treatment that use cellular or genetic material with the goal of treating a disease or a…

Cancer-cell-immunotherapy-research Blogs
Read article Why Stimulate Cells for Flow Cytometry?

Many flow cytometry users are happy to start an experiment with a general protocol and a question about their specimen -- Will my cells make more cytokines or express more markers after activation? Will my cells respond to a novel immunotherapeutic drug candidate?

therapeutic_antibodies_featured Blogs
Read article Flow Cytometry for Therapeutic Antibody Assessment

Immunotherapy research is a rapidly expanding field with a pipeline of monoclonal antibodies in development to treat a range of cancers and autoimmune diseases. The mechanism of action (MOA) used by an antibody to mediate a therapeutic response must be fully defined to enable a candidate antibody to advance down the preclinical development pipeline. It is also required for all antibodies used in clinical research and regulatory IND filings in order to optimize dosing and assess the risk of detrimental side effects.