Podcasts
Episode 17 of The Conversational Flow podcast, hosted by Brian Wile and Adam Cotty, dives into the evolving landscape of flow cytometry networking and regulatory guidance, where they analyze recent FDA biomarker validation guidance, comparing it to existing industry standards like CLSI H62. Our hosts explore the challenges of harmonizing flow cytometry…
Blogs
If you have trained in the field of immunology, it may not be uncommon to emerge with a self-characterization as either a “B-cell immunologist” or a “T-cell immunologist.” Historically, this distinction arose from years of specialization and the degrees of separation between T-cell and B-cell biology research. Approaches to therapeutic…
Podcasts
In episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology…
Podcasts
In this exciting 15th episode of The Conversational Flow podcast, titled “Fantastic Fluorophores and Where to Find Them,” hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as…
Posters & Papers
This infographic explores the key trends in flow cytometry, software and instrumentation based on results from a recent Spotlight survey. It highlights the top challenges for biomarker analysis using flow cytometry, including lack of standardized control materials, sourcing a suitable laboratory and uncertain regulatory expectation, as well as what the…
Posters & Papers
Please download this poster, “Validation of a 15-Color Spectral Flow Cytometry Panel for Globally Harmonized Comprehensive Leukocyte Profiling in Human Whole Blood: Translational and Clinical Applications “ CYTEK_ValidatedPanels_EBF2024_20241118Download…
Podcasts
A flow cytometry backbone panel is a set of antibodies that can be used as a starting point for identifying cell types, and then supplemented with additional markers. On the most recent episode of “The Conversational Flow”, our hosts, Brian and Adam, spend some time together as they answer the questions…
Webinars
Webinar Description: Acquire a deeper understanding of Receptor Occupancy (RO) assays as measured by flow cytometry. We will discuss the fundamental considerations for RO method design, development, and validation. Within each of these areas, Dr. Evans highlights critical areas of consideration which can impact your ability to robustly quantify Receptor Occupancy within…
Blogs
Intracellular cytokine staining (ICS) is a functional immunology assay that uses flow cytometry to assess cytokine production by individual cells. Cytokines play a critical role in developing both physiologically appropriate and pathological immune responses. Interferon-γ (IFN-γ) is an excellent example of this, where it has a key role in antiviral…
Webinars
Webinar Description: KCAS Bio will present results from a recent validation of two IP panels on the Cytek Aurora in PBMCs. We have analyzed the impact of different fixation buffers on the efficacy of reference controls over time, and we will explore how to help improve workflow standards and process…
Podcasts
During the most recent episode of “The Conversational Flow” podcast, our hosts Brian and Adam talk about those times when a smaller panel might be desirable over a larger panel. To dive deep into this discussion and really analyze all the angles of these questions, the guys have invited a…
Blogs
KCAS Bio has embarked on a global initiative to harmonize its spectral flow cytometry services across four labs in three countries, collaborating with Crux Biolabs and Cytek Biosciences. This effort ensures standardized flow cytometry services across sites in the U.S., Europe, and Australia. As trials increasingly span multiple regions, global…