
Clients typically will come to us saying that they have a therapy, and it is going to address these targets, this disease, to treat certain patients. They want to know how we can best understand what’s happening and how the immune system will respond. We need to know what cells…

One of the coolest things we’re doing here at KCAS Bio is definitely validating new instruments and new software. We start off with the Cytek systems of course, and then we’re adding in FCS Express, we’re applying both of those tools ’cause that’s really all they are at the…

KCAS has recently moved from a space that was extremely tight – even for the operations we had at the time – to an enormous new modern lab building that is purpose-built for the type of work that allows all of our workflows to be more efficient, more scalable,…

For the last decade or so, the outsourcing of crucial research functions by pharmaceutical and biotechnology companies has become increasingly common and has resulted in the rapid growth of the Contract Research Organization (CRO) industry. But the selection of the best CRO partner to work on your critical research programs…

The newest episode of “The Conversational Flow” has Brian and Adam talking about the concepts around Receptor Occupancy and all the deceptively simple questions people often have about them, as well as the important but sometimes difficult answers to those questions. They talk about the biology of receptors and the…

Flow Cytometry has been an invaluable tool for scientific advancement in immunology, oncology, stem cell research, infectious disease, vaccines, and drug development research. As a versatile and powerful technique, it can be used in various ways and tailored to meet your research needs. Applications include precise evaluation of cell…

During this newest episode of “The Conversational Flow”, Brian and Adam discuss cell sorting and the pivotal role it plays in molecular biology applications – enabling researchers to isolate specific cell populations from complex mixtures, as well as a number of other benefits. Our hosts dive into the importance of…

For the 4th episode of “The Conversational Flow” podcast, Brian and Adam discuss spectral flow; something really near and dear to their hearts. This is a topic both of our hosts have been genuinely interested in since they really became aware of it, at which time they immediately…

Immunogenicity refers to the ability of a substance, such as an antigen or a vaccine, to provoke an immune response in an organism. The recognition of the substance as foreign triggers an immune response, which involves the production of antibodies and the activation of immune cells to fight against or…

Two of the scientific experts from KCAS Bio have been leaders in determining the direction of qPCR and ddPCR technology for the industry. Carrie Vyhlidal, PhD and Jonathan Mercier are both part of the American Association of Pharmaceutical Scientists’ working group for PCR-based methodology, and they have recently…

Flow cytometry is a highly sophisticated laboratory technique. Scientists use this procedure to analyze and quantify certain physical and chemical characteristics of cells or particles. In recent years, the prominence of flow cytometry has grown significantly, and understanding why is pivotal. The recognition of the technique’s importance, especially in the…

There are a number of different guidances for Flow Cytometric Assay Validation, so for episode #3 of “The Conversational Flow” podcast, Brian and Adam go into great detail on how we perform validations at KCAS, and under what context we do so – and why. In this episode,…