Therapeutic Area - Cancer/Oncology Solutions
Immuno-oncology is a growing field. The goal is to augment the patient’s immune system to attack the cancer cells. The current lines of treatment for cancer are radiation, chemotherapy, and surgical resection. If these treatments do not work, physicians can seek alternative treatments, such as immune-oncology therapeutics. Two emerging immune-oncology therapeutic modalities are saving lives: antibody drug conjugates (ADCs) and cellular therapies.
We can help with the success of your oncology project
KCAS has the expertise to support the Immuno-oncology field. We have expertise in flow cytometry, ELISPOTs, cell based assays and multiple biomarkers for the development of new drugs. Whether it is in-vitro discovery method or support of a phase III trial, we can assist you. We provide reliable and defendable data while continuing to help our partners develop drugs for the advancement of world health.

KCAS Cancer/Oncology Services
The translation of an assay from Discovery to Preclinical/Clinical is an important part of dru…
Colorimetric analysis is a method of determining the concentration of a chemical element or ch…
Methods transferred into a new laboratory need to be re-established for regulatory compliance….
Affinity capture elution (ACE) is a method used in detecting ADA to increase the assay drug to…
Aggregate analysis is done to identify potential protein aggregation that can contribute to th…
The analysis of free amino acids (20 naturally occurring) in plasma or other biological matric…
Bioavailability (BA) is the percentage that a drug or its pro-drug form is absorbed into the g…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
A significant number of drugs contain a chiral center that allows the compound to properly fit…
Critical reagents are essential components of analytical methods whose unique characteristics…
Should define what it is first… ie Bridging Validation is a run when one is trying to move fro…
The accelerated pace within industry for quick “go / no-go” decisions in drug development, nec…
KCAS provides dose form analysis (DFA) for clinical and non-clinical investigations, with a wi…
Flow cytometry is a technique used to detect and measure physical and chemical characteristics…
Fluorescence is used mainly for measuring compounds in solution, or in the case of flow cytome…
Hybrid LCMS is a technique which combines an enrichment step (typically an antibody enrichment…
All biotherapeutics will need to undergo immunogenicity assessment sometime in their drug deve…
Clinical Sample Kits at KCAS are more than just clinical supplies for the collection of PK sam…
Luminescence immunoassays use the low-temperature emission of light (as by a chemical or physi…
At KCAS, methods are developed with a fit-for-purpose design in mind, based on our Client’s ne…
A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed t…
KCAS has extensive experience in validating methods in a wide range of bioanalytical platforms…
Multi-plex analysis of biomarkers is a powerful tool for screening of many analytes in a small…
KCAS’ Kit preparation service can provide kits for sample collection for Pre-Clinical/ Non-Cl…
The discovery phase in drug development requires rapid and reliable data in making key decisio…
PD Analysis is the assistance with design, regulatory requirements and final data interpretati…
Biomarkers come in many favors. They can vary from serum/plasma analytes to the measurement of…
Pharmacokinetics (PK) is the determination of the extent of Absorption, Distribution, Metaboli…
Polymeric conjugates are polymer backbones used as delivery systems for drugs conjugated to th…
The extent to which a drug binds to plasma proteins can range from neglible to 99.9+% with com…
The Laboratory Collection Manual provides biological sample collection, processing, storage an…
Biomarkers come in many flavors and can be used as alternatives for assessing the functionalit…
Size Exclusion Chromatography (SEC) is a chromatography method that allows for the separation…
Pharmacological activity of a drug molecule is influenced by many factors. The way a molecule…
Time resolved fluorescence (TRF) relies on the use of very specific fluorescent molecules call…
Tissue bioanalysis is an essential area in understanding the extent of drug distribution, meta…