Blogs
Intracellular cytokine staining (ICS) is a functional immunology assay that uses flow cytometry to assess cytokine production by individual cells. Cytokines play a critical role in developing both physiologically appropriate and pathological immune responses. Interferon-γ (IFN-γ) is an excellent example of this, where it has a key role in antiviral…
webinars
Webinar Description: KCAS Bio will present results from a recent validation of two IP panels on the Cytek Aurora in PBMCs. We have analyzed the impact of different fixation buffers on the efficacy of reference controls over time, and we will explore how to help improve workflow standards and process…
Podcasts
During the most recent episode of “The Conversational Flow” podcast, our hosts Brian and Adam talk about those times when a smaller panel might be desirable over a larger panel. To dive deep into this discussion and really analyze all the angles of these questions, the guys have invited a…
Blogs
KCAS Bio has embarked on a global initiative to harmonize its spectral flow cytometry services across four labs in three countries, collaborating with Crux Biolabs and Cytek Biosciences. This effort ensures standardized flow cytometry services across sites in the U.S., Europe, and Australia. As trials increasingly span multiple regions, global…
Blogs
We are thrilled to announce a major milestone in the evolution of our global clinical support services. After months of detailed planning, collaboration, and execution, we’ve successfully integrated spectral flow cytometry at our KCAS Bio sites in Philadelphia, PA, USA; Lyon, France; and Crux Biolabs, our…
Podcasts
In the 12th episode of “The Conversational Flow” podcast, Brian and Adam welcome two special guests – Sean Burke of Denovo Software and Ryan Brinkman of Dotmatics – who join them to discuss the answers to a number of specific questions about High Content Analysis: How can we manage and…
Blogs
The exploration of Targeted Protein Degraders (TPD) as a therapeutic modality began over twenty years ago. Since then, research and development in this field have steadily advanced. Starting in 2019, rationally designed small molecule TPDs entered clinical trials. This innovative therapeutic modality utilizes the cells’ endogenous protein degradation machinery to…
webinars
In the fast-paced world of drug development, the ability to produce accurate and reproducible data is paramount. That’s why staying updated with the latest best practices in flow cytometry is crucial. Our webinar, “Evolving Best Practices: Considerations for Conventional and Spectral Flow,” dives deep into the rapidly advancing field of…
webinars
In the rapidly advancing world of flow cytometry, staying ahead of the curve is essential for driving impactful research and drug development. Our panel discussion, “Evolving Best Practices in High-Complexity Flow Cytometry,” sheds light on the latest developments that can enhance and accelerate your research efforts. Flow cytometry has long…
Podcasts
During this special episode of “The Conversational Flow” our hosts, Brian and Adam, welcome two guests: John Bucksath, CEO of KCAS Bio, and Stefan Cross, CEO of Crux Biolabs. These two guests discuss the elements and advantages of their organizations’ new partnership between KCAS’ US and European locations and Crux’s…
Blogs
Spectral flow cytometry and the growing array of commercially available fluorophores have led to the development of increasingly complex immunophenotyping panels. Generating robust data depends not only on a strong panel design but also on the use of appropriate reference controls and a solid understanding of spectral unmixing principles. …
Podcasts
When it comes to flow cytometry instrumentation, there are a number of things that can be different. You may have different types of lasers, you might have a different path for the laser to follow to get to the detector, you can have different actual detectors, different filters in front…