Podcasts
In this milestone 20th episode of “The Conversational Flow” podcast, hosts Adam and Brian dive into impactful developments across oncology, regulatory science, and bioanalytical innovation. The episode begins with a highlight of a recent major Keytruda study showing the first significant improvement in head and neck squamous cell carcinoma outcomes…
Blogs
In drug development, the journey from target identification to clinical candidate selection involves a series of critical steps, including compound screening, lead optimization, and pre-clinical testing. Each stage helps narrow the pool of potential therapeutics, with the goal of identifying the most promising candidates for clinical evaluation. Given the time,…
Blogs
At KCAS Bio, we offer expert flow cytometry services designed to support the evolving bioanalytical needs of immunology and biomarker projects for drug development. Whether you’re working in preclinical or clinical settings, our validated off-the-shelf panels save time, reduce risk, and deliver high-quality, reproducible data you can trust. Extensive Portfolio…
Podcasts
In the 19th episode of “The Conversational Flow”, our hosts, Brian and Adam, dive into the utility and innovation behind backbone panels in spectral flow cytometry, spotlighting a recent paper from BMS that presents a robust, flexible assay designed for immune monitoring using the Aurora platform. They discuss how backbone…
Posters & Papers
Discover in this poster presented by David Ambrose at WRIB 2025, our work on the Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational and Clinical Applications. Spectral Flow Cytometry Panel | KCAS Bio…
Blogs
Quantitative flow cytometry (QFCM) is a specialized technique that enables precise measurement of the absolute number of specific molecules (e.g., receptors, antigens, or intracellular targets) on individual cells or particles. Understanding flow cytometry is essential, as standard methods typically provide qualitative data, where the relative fluorescence intensity is used to…
Blogs
Modern immunology research requires high-complexity panels available wherever the patients are located. Deploying advanced flow cytometry instruments and panels across multiple global sites is therefore a transformative step in harmonizing immunological research and clinical trials. KCAS Bio has worked closely with Cytek to make this a reality by validating the…
Podcasts
In this engaging episode of the podcast, hosts Brian Wile and Adam Cotty welcome special guests Michael Naso, Hillary Quinn, and Barry Morse from The Therapeutic Innovations Group—a powerhouse team of scientists and biotech veterans with decades of experience across biologics, small molecules, and cell therapy. The conversation dives deep…
Podcasts
Episode 17 of The Conversational Flow podcast, hosted by Brian Wile and Adam Cotty, dives into the evolving landscape of flow cytometry networking and regulatory guidance, where they analyze recent FDA biomarker validation guidance, comparing it to existing industry standards like CLSI H62. Our hosts explore the challenges of harmonizing flow cytometry…
Blogs
If you have trained in the field of immunology, it may not be uncommon to emerge with a self-characterization as either a “B-cell immunologist” or a “T-cell immunologist.” Historically, this distinction arose from years of specialization and the degrees of separation between T-cell and B-cell biology research. Approaches to therapeutic…
Podcasts
In episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology…
Podcasts
In this exciting 15th episode of The Conversational Flow podcast, titled “Fantastic Fluorophores and Where to Find Them,” hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as…