Advancing Drug Discovery: The Power of Flow Cytometry in Compound Screening Blogs
Read article Advancing Drug Discovery: The Power of Flow Cytometry in Compound Screening

In drug development, the journey from target identification to clinical candidate selection involves a series of critical steps, including compound screening, lead optimization, and pre-clinical testing. Each stage helps narrow the pool of potential therapeutics, with the goal of identifying the most promising candidates for clinical evaluation. Given the time,…

Off-The-Shelf Flow Cytometry Panels for Immune Monitoring Blogs
Read article Off-The-Shelf Flow Cytometry Panels for ImmuneMonitoring

At KCAS Bio, we offer expert flow cytometry services designed to support the evolving bioanalytical needs of immunology and biomarker projects for drug development. Whether you’re working in preclinical or clinical settings, our validated off-the-shelf panels save time, reduce risk, and deliver high-quality, reproducible data you can trust. Extensive Portfolio…

KCAS-podcast-thumb_TCF-019 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #19: “Building on Backbone Panels: Standardization, Speed, and Integration”

In the 19th episode of “The Conversational Flow”, our hosts, Brian and Adam, dive into the utility and innovation behind backbone panels in spectral flow cytometry, spotlighting a recent paper from BMS that presents a robust, flexible assay designed for immune monitoring using the Aurora platform. They discuss how backbone…

SpectralFlowCytometryPanel_KCASBio Posters & Papers
Read article Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational & Clinical Applications

Discover in this poster presented by David Ambrose at WRIB 2025, our work on the Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational and Clinical Applications. Spectral Flow Cytometry Panel | KCAS Bio…

Quantitative Flow Cytometry: Applications & Benefits Blogs
Read article Quantitative Flow Cytometry: Applications & Benefits

Quantitative flow cytometry (QFCM) is a specialized technique that enables precise measurement of the absolute number of specific molecules (e.g., receptors, antigens, or intracellular targets) on individual cells or particles. Understanding flow cytometry is essential, as standard methods typically provide qualitative data, where the relative fluorescence intensity is used to…

Driving Innovation Globally with Multisite Spectral Flow Cytometry Blogs
Read article Driving Innovation Globally with Multisite Spectral Flow Cytometry: Global Implementation of a Validated Flow Cytometry Panel

Modern immunology research requires high-complexity panels available wherever the patients are located. Deploying advanced flow cytometry instruments and panels across multiple global sites is therefore a transformative step in harmonizing immunological research and clinical trials. KCAS Bio has worked closely with Cytek to make this a reality by validating the…

KCAS-podcast-thumb_TCF-018 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #18: “Flow Cytometry & Cell Therapy: One Cell Can Make a World of Difference”

In this engaging episode of the podcast, hosts Brian Wile and Adam Cotty welcome special guests Michael Naso, Hillary Quinn, and Barry Morse from The Therapeutic Innovations Group—a powerhouse team of scientists and biotech veterans with decades of experience across biologics, small molecules, and cell therapy. The conversation dives deep…

KCAS-podcast-thumb_TCF-017 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #17: “Flow Validations and Guidance Document Changes in 2024-2025”

Episode 17 of The Conversational Flow podcast, hosted by Brian Wile and Adam Cotty, dives into the evolving landscape of flow cytometry networking and regulatory guidance, where they analyze recent FDA biomarker validation guidance, comparing it to existing industry standards like CLSI H62. Our hosts explore the challenges of harmonizing flow cytometry…

KCAS-blog-thumb_2025-01_Spectral Panel for B Cells Blogs
Read article Advanced Flow Cytometry Solutions for Drug Development: a Focus on B Cells (Part 1)

If you have trained in the field of immunology, it may not be uncommon to emerge with a self-characterization as either a “B-cell immunologist” or a “T-cell immunologist.” Historically, this distinction arose from years of specialization and the degrees of separation between T-cell and B-cell biology research.  Approaches to therapeutic…

KCAS-podcast-thumb_TCF-016 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #16: “The Role of Flow in Drug Autoimmune Indication Research”

In episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology…

KCAS-podcast-thumb_TCF-015 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #15: “Fantastic Fluorophores and Where to Find Them (w/ Kelly Lundsten)”

In this exciting 15th episode of The Conversational Flow podcast, titled “Fantastic Fluorophores and Where to Find Them,” hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as…

Bioanalysis-zone-spotlight-3 Posters & Papers
Read article Evolving Best Practices in Flow Cytometry to Support Biomarker Analysis in Drug Development

This infographic explores the key trends in flow cytometry, software and instrumentation based on results from a recent Spotlight survey. It highlights the top challenges for biomarker analysis using flow cytometry, including lack of standardized control materials, sourcing a suitable laboratory and uncertain regulatory expectation, as well as what the…