Please download this poster, “Comparative Evaluation of Ligand Binding Assay Platforms for BiomarkerQuantification: Critical Considerations for Ensuring Data Quality and Project Success” LBAPlatforms_EBF2024_Poster_vfDownload…

KCAS Bio is excited to announce our participation in the Society of Toxicology (SOT) Annual Meeting and ToxExpo, taking place in Orlando, Florida on March 16th-20th. As one of the largest gatherings of toxicologists and life sciences professionals, this event offers a unique platform to connect with leaders in toxicology…

A flow cytometry backbone panel is a set of antibodies that can be used as a starting point for identifying cell types, and then supplemented with additional markers. On the most recent episode of “The Conversational Flow”, our hosts, Brian and Adam, spend some time together as they answer the questions…

KCAS Bio is thrilled to announce our attendance at the upcoming J.P. Morgan Healthcare Conference, a premier gathering that draws top leaders, decision-makers, and innovators from across the life sciences and healthcare industries. As we join this influential event in San Francisco, KCAS Bio is eager to connect with industry…

The Importance of GLP Compliance Certificate for Bioanalytical CROs We are proud to celebrate the one-year anniversary of our Good Laboratory Practice (GLP) Test Facility based in Lyon (France), dedicated to…

Immunogenicity, why do we keep talking about it? Immunogenicity can, in the simplest of terms, be described as a subject’s ability to generate antibodies specific to the dosed protein therapeutic. While stating it this way understates the complexity of the immune system and the methods needed to detect and characterize…

Webinar Description: Acquire a deeper understanding of Receptor Occupancy (RO) assays as measured by flow cytometry.  We will discuss the fundamental considerations for RO method design, development, and validation.  Within each of these areas, Dr. Evans highlights critical areas of consideration which can impact your ability to robustly quantify Receptor Occupancy within…

KCAS Bio is excited to sponsor the upcoming Pharmaceutical & BioScience Society (PBSS) workshop, “Current State of Bioanalysis for Biologics and Cell/Gene Therapy Products: Refining Established Approaches for New Complex Therapies,” in Foster City, California. Dawn Dufield, Ph.D., will be presenting “Bioanalysis for Biologics and Cell/Gene Therapy Products…

Intracellular cytokine staining (ICS) is a functional immunology assay that uses flow cytometry to assess cytokine production by individual cells. Cytokines play a critical role in developing both physiologically appropriate and pathological immune responses. Interferon-γ (IFN-γ) is an excellent example of this, where it has a key role in antiviral…

It’s conference season! This is a busy, busy time of the year for the entire industry, when everyone comes together from around the world to share, listen and discuss the changes and advancements taking place in the business and science of the pharma and biotech space. During this episode of…

Oligonucleotide therapeutics have recently gained popularity as noted by recent increases in regulatory approvals of oligonucleotides as drugs, novel liquid nanoparticle delivery approaches, and on-target specificity. In the development of bioanalytical assays, there are many challenging aspects to consider when quantitating oligonucleotides, such as non-specific binding, stability, efficient ionization, sequence…

Webinar Description: KCAS Bio will present results from a recent validation of two IP panels on the Cytek Aurora in PBMCs. We have analyzed the impact of different fixation buffers on the efficacy of reference controls over time, and we will explore how to help improve workflow standards and process…