Clients typically will come to us saying that they have a therapy, and it is going to address these targets, this disease, to treat certain patients. They want to know how we can best understand what’s happening and how the immune system will respond. We need to know what cells…
One of the coolest things we’re doing here at KCAS Bio is definitely validating new instruments and new software. We start off with the Cytek systems of course, and then we’re adding in FCS Express, we’re applying both of those tools ’cause that’s really all they are at the…
KCAS has recently moved from a space that was extremely tight – even for the operations we had at the time – to an enormous new modern lab building that is purpose-built for the type of work that allows all of our workflows to be more efficient, more scalable,…
For the last decade or so, the outsourcing of crucial research functions by pharmaceutical and biotechnology companies has become increasingly common and has resulted in the rapid growth of the Contract Research Organization (CRO) industry. But the selection of the best CRO partner to work on your critical research programs…
Rosalind Franklin: Unveiling the DNA Helix and Beyond She is known for the celebrated photo 51 She is famous for her X-rays An American university and an English research institute bear her name Her name is Rosalind Franklin. Her crucially important X-ray crystallography work was key to…
Flow Cytometry has been an invaluable tool for scientific advancement in immunology, oncology, stem cell research, infectious disease, vaccines, and drug development research. As a versatile and powerful technique, it can be used in various ways and tailored to meet your research needs. Applications include precise evaluation of cell…
You might be asking what type of laboratory my biomarker assay requires or what level of qualification or validation my assay needs. These are complex questions which there continues to be a significant amount of misunderstanding around. Fortunately, KCAS Bio has extensive experience with both biomarker development and qualification/validation to…
Immunoaffinity LC-MS/MS or hybrid LC-MS/MS is an approach that has been gaining a lot of traction in the past several years. The technique allows the quantitation of low-level analytes (proteins or peptides in many cases) in biological matrices with exquisite selectivity and sensitivity. Many pharmaceutical companies are trying to expand…
In the complex and dynamic bioanalytical landscape of antibody-drug conjugate (ADC) services, where often time is critical and every research dollar counts, hybrid technology is quickly emerging as a game-changer. Hybrid offers a spectrum of advantages that redefine traditional approaches to bioanalytical ADC drug development. At the forefront of these…
If you are part of the Biotech/Pharma community, you may be familiar with the (J.P. Morgan) JPM Healthcare Conference that takes place annually in January and typically in San Francisco. This was the 42nd Annual JPM Healthcare Conference and it is the world’s largest healthcare symposium. This year the mood…
In the fast-paced and highly competitive landscape of contract research organizations (CROs) — where data serves as the cornerstone for all operations — robust data security practices are paramount. CROs play a pivotal role in the biopharma industry. They serve as trusted partners for conducting crucial studies and managing sensitive…
Immunoassays are bioanalytical methods that generally use antibodies to detect and quantify specific analytes, often proteins, in biological samples. The process involves the capture of a target protein by an immobilized antibody, followed by its detection with another antibody conjugated either to enzymes, such as phosphatase alkaline or horseradish peroxidase…