Therapeutic Area - Infectious Diseases & Vaccines Solutions
It’s important to choose a team that has the right kind of therapeutic experience for your infectious disease and vaccine solutions testing. In a post-covid world, there have been a number of CRO’s popping up who claim to be specialists in the vaccine space, but very few have the broad range of expertise in infectious disease and vaccine development to develop a successful program for your project.
KCAS has a wide array of platforms and techniques we can apply to your project
KCAS can help in the current environment by monitoring the status of the immune system both during and after infection in order to understand the infection/recovery pathway, evaluate relapse factors versus true recovery, and the mechanism of cytokine response. KCAS stands ready to perform flow cytometric immunophenotyping, cytokine profiling in vitro and in vivo, as well as retrospective studies. KCAS has experience with whole blood, fresh, frozen or fixed PBMCs, lymphoid tissue, respiratory samples, serum, and plasma.
KCAS Infectious Diseases & Vaccines Services
The translation of an assay from Discovery to Preclinical/Clinical is an important part of dru…
Colorimetric analysis is a method of determining the concentration of a chemical element or ch…
Methods transferred into a new laboratory need to be re-established for regulatory compliance….
Affinity capture elution (ACE) is a method used in detecting ADA to increase the assay drug to…
Bioavailability (BA) is the percentage that a drug or its pro-drug form is absorbed into the g…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Cell based assays are highly specialized in vitro methods that can evaluate the functional and…
Flow cytometry is a technique used to detect and measure physical and chemical characteristics…
Fluorescence is used mainly for measuring compounds in solution, or in the case of flow cytome…
Hybrid LCMS is a technique which combines an enrichment step (typically an antibody enrichment…
All biotherapeutics will need to undergo immunogenicity assessment sometime in their drug deve…
Clinical Sample Kits at KCAS are more than just clinical supplies for the collection of PK sam…
Luminescence immunoassays use the low-temperature emission of light (as by a chemical or physi…
At KCAS, methods are developed with a fit-for-purpose design in mind, based on our Client’s ne…
A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed t…
KCAS has extensive experience in validating methods in a wide range of bioanalytical platforms…
The discovery phase in drug development requires rapid and reliable data in making key decisio…
PD Analysis is the assistance with design, regulatory requirements and final data interpretati…
Biomarkers come in many favors. They can vary from serum/plasma analytes to the measurement of…
Pharmacokinetics (PK) is the determination of the extent of Absorption, Distribution, Metaboli…
Tissue bioanalysis is an essential area in understanding the extent of drug distribution, meta…