This webinar is a collaboration between Sciex and KCAS Bio. Exploring cutting-edge methods for analyzing oligonucleotides in biological matrices. Oligonucleotide therapeutics have gained recent popularity given their vast applications in genetic disorders, cancers and infectious diseases. There are many challenges when developing bioanalytical methods for the quantitation of oligonucleotides, including…
In this discussion, our panelists examine oligonucleotide bioanalysis assessment strategies, including quantification via LBA, LC–MS/MS and hybrid assays, as well as the emerging technologies and the future direction of this rapidly evolving field. In 1998, the first oligonucleotide therapy was approved for commercial use and since then many more have…