Discover in this poster presented by Andrew Bergdorf at the American Society for Mass Spectrometry (ASMS) Conference in 2026 about how we developed a streamlined, high-throughput proteomics workflow for human heart tissue that reduces sample preparation time while maintaining robust and reproducible biomarker detection.

Key optimizations in homogenization and digestion, including sonication and enzyme selection, significantly improved peptide yield, sequence coverage, and consistency across samples. The resulting method enables reliable multiplexed biomarker analysis using DDA-based data acquisition with strong performance on abundant cardiac proteins.

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