Small Molecules
Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight (< 900 daltons) organic compound that may regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules. Small molecules may be used as research tools to probe biological function as well as leads in the development of new therapeutic agents. Some can inhibit a specific function of a protein or disrupt protein–protein interactions.
Small molecules can have a variety of biological functions or applications, serving as cell signaling molecules, drugs in medicine, pesticides in farming, and in many other roles. These compounds can be natural (such as secondary metabolites) or artificial (such as antiviral drugs); they may have a beneficial effect against a disease (such as drugs) or may be detrimental (such as teratogens and carcinogens).
SERVICES
- Bioavailability / Bioequivalence (BA/BE) Studies
- Clinical Sample Analysis
- Dose Formulation Analysis
- Method Development
- Pharmacodynamic (PD) Biomarkers
- Pharmacokinetic / Toxicokinetic (PK/TK) Analysis
- Targeted Metabolite ID
- Non-Clinical GLP Sample Analysis
- Chiral Assay Development, Qualification & Validation
- Assay Translation (Species and Fluids)
- Method Transfer
- Critical Reagent Characterization
- Discovery Support
- Polymeric Conjugate Testing
- Method Qualification
- Critical Reagents
- Method Validation
- Tissue Bioanalysis
- Multi-Plex Analysis
- Non-GLP Sample Analysis
- Molecular Services