Posts by KCAS Bio
Podcasts
The main discussion in Episode #102 explores what KCAS scientific advisors are hearing from customers as face-to-face visits and industry interactions increase. The conversation highlights a major shift toward more complex therapeutics and targeted delivery strategies, including conjugates, protein shuttles, in vivo gene therapies, and technologies designed to cross…
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Blogs
Poster Title: Method Development and Validation for the Determination of Two Protein Biomarkers by Multiplexed Online and Offline Hybrid LC-MS/MS in Human Heart Tissue Can you explain your role at KCAS Bio? I am a Scientist 1 at KCAS Bio in the Mass Spectrometry Bioanalysis Method Development group. In…
Podcasts
Episode #32 of The Conversational Flow explores several significant developments shaping the flow cytometry and biopharmaceutical industries, including advances in antibody drug conjugates (ADCs), questions surrounding circadian timing in cancer treatment, and major life sciences acquisitions. Our hosts, Brian and Adam, discuss how improvements in ADC linker technology and…
Podcasts
The main discussion in Episode #101 of “The Weekly Bioanalysis” focuses on how bioanalytical testing continues to evolve alongside increasingly complex drug modalities, with our co-hosts, Dom and John, exploring the technologies, methodologies, and regulatory trends shaping modern bioanalytical laboratories. They discuss how advances in mass spectrometry, including the…
Blogs
What are functional assays? Understanding the interactions between drugs and biological systems is critical for the success of a new drug. One key tool in this process is functional assays. Functional assays in drug development are customized assays that evaluate the impact of drugs on the functionality of cells.
Podcasts
In this special 100th episode of The Weekly Bioanalysis, hosts John Perkins and Dominic Warrino are joined on camera by KCAS Bio CEO John Bucksath and Chief Commercial Officer Amy Mize to celebrate a major milestone. Together, they reflect on the podcast’s origins during the uncertainty of the COVID-19…
Podcasts
Episode 31 of The Conversational Flow Podcast dives deep into some of the most exciting developments currently shaping the future of cell therapy, flow cytometry, and AI-driven drug development. Our hosts, Brian and Adam, discuss major advances in allogeneic and in vivo CAR-T therapies, including how new manufacturing platforms…
Blogs
Why Cell Stimulation Matters in Flow Cytometry Many flow cytometry users are happy to start an experiment with a general protocol and a question about their specimen: Will my cells make more cytokines or express more markers after activation? In a healthy person, immune cells like B cells, T cells,…
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Blogs
In biomarker-driven drug development, selecting the right assay format is critical for generating reliable data that informs scientific and clinical decisions. Whether quantifying proteins, immune cell subsets, or complex molecular signatures, the choice between off-the-shelf and customized assays has direct implications for timelines, costs, and how well the assay…
Blogs
The Importance of GLP Compliance Certificate for Bioanalytical CROs We are proud to celebrate the one-year anniversary of our Good Laboratory Practice (GLP) Test Facility based in Lyon (France), dedicated to…