Posts by Christine Bain, Ph.D.

Christine brings more than 25 years of experience in immunology and coordination of immune monitoring studies in the context of clinical trials in oncology and infectious diseases. She is now in charge of scientific affairs, from the development of internal R&D programs to the implementation of external collaborative projects with our partners.

KCAS-blog-thumb_2024-03A_OlfactoryBiomarkers Blogs
Read article The Power of Our Fifth Sense

In the scientific field, the often neglected fifth sense, the sense of smell, contributes to broadening our understanding of various phenomena, particularly in the field of biomarkers.Here, we will guide you along our lines of thought on the importance of our olfactory sense, and how it contributes to scientific exploration…

KCAS-blog-thumb_2024-AB Blogs
Read article Ultrasensitive Immunoassays: From cutting-edge technological innovation to proof of utility

Immunoassays are bioanalytical methods that generally use antibodies to detect and quantify specific analytes, often proteins, in biological samples. The process involves the capture of a target protein by an immobilized antibody, followed by its detection with another antibody conjugated either to enzymes, such as phosphatase alkaline or horseradish peroxidase…

KCAS-blog-thumb_2023-11A_immunogenicity Blogs
Read article Immunogenicity: A Comparative Analysis of Assessment Methods

Immunogenicity refers to the ability of a substance, such as an antigen or a vaccine, to provoke an immune response in an organism. The recognition of the substance as foreign triggers an immune response, which involves the production of antibodies and the activation of immune cells to fight against or…

3d illustration lymphocytes, t cells or cancer cells Blogs
Read article ELISpot Assay: Versatile Applications and Common Challenges to Overcome

ELISpot (Enzyme-linked immunosorbent spot) is an immunoassay-based technique used to quantify cells that are capable of secreting proteins, including cytokines, cytotoxic molecules, and antibodies, when stimulated with the appropriate antigen. Initially designed to monitor the frequency of circulating antigen-specific memory B-cells, it is now commonly used to determine the frequency…

KCAS-blog-thumb_2023-09A_LBAs-Plethora Blogs
Read article Ligand Binding Assays: a Plethora of Technologies to Address Your Projects’ Requirements

Ligand binding assays (LBAs) have been our core activity for decades. LBAs are commonly used to measure interactions between two proteins, a ligand and its receptor, a monoclonal antibody (mAb) and its target, or biologics and Anti-Drug Antibodies (ADA). Throughout the…

KCAS-blog-thumb_2023-08D_Soluble-Biomarkers Blogs
Read article Soluble Biomarkers from KCAS: a Global Perspective

A biomarker is a defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or biological responses to an exposure or intervention, including therapeutic interventions(1). With the development of innovative and personalized therapies, biomarker tracking is increasingly important to support the clinical development…