Posts by Cheikh Kane, Ph.D.

Cheikh Kane, PhD is currently the VP BioPharma Sciences at KCAS Bio where his teams are focused on bioanalytical LBA (PK, ADA and BM), Cell Based NAB (Neutralizing antibody assays) and Molecular to support drug development programs for biologics. Dr. Kane has more than two decades of experience in the bioanalytical and biomarker fields and related strategies spanning from Biopharmaceutical/Biotechnology industry to the CRO business. At KCAS Bio he leads strategic and technical initiatives that drive innovation in bioanalytical, biomarker and molecular sciences and expands the company’s capabilities.

ADC Antibody Drug Conjugate Molecule Linker Payload Protein Posters & Papers
Read article Quantification of antibody–drug conjugate PYX-201 in rat and monkey plasma via ELISA and its application in preclinical studies
Quantification of antibody–drug conjugate PYX-201 in rat and monkey plasma via ELISA and its application in preclinical studies

This case study describes the development and validation of an ELISA method to quantify total antibody (tAb) from PYX-201, an investigational antibody-drug conjugate (ADC) developed by Pyxis Oncology. The assay was validated in rat and monkey plasma and used to support preclinical studies and an IND filing. The method…

Enzyme-linked immunosorbent assay (ELISA), Immunology testing method in laboratory Posters & Papers
Read article Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies
Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies

This case study describes the development and validation of an ELISA method to quantify total antibody (tAb) from PYX-201, an investigational antibody-drug conjugate (ADC) developed by Pyxis Oncology. The assay was validated in rat and monkey plasma and used to support preclinical studies and an IND filing. The method…

KCB-poster_WRIB-2024_ISR-MAB-error-reduction Posters & Papers
Read article Automating Selection for Incurred Sample Reanalysis: A Meta-Analytical-Based Algorithm for Error Reduction
Automating Selection for Incurred Sample Reanalysis: A Meta-Analytical-Based Algorithm for Error Reduction

Please download this poster, “Automating Selection for Incurred Sample Reanalysis: A Meta-Analytical-Based Algorithm for Error Reduction”