Ophthalmology CRO Services
KCAS Bio has experience in preclinical ophthalmic research, ranging from identification and procurement of compounds to determining efficacy, tolerability, and PK studies. We give you the milestone data you need to make important decisions in the early stages of your ophthalmologic product development.
Complex ophthalmology studies demand specialist expertise
When developing products for the eye, your project needs a CRO with specialist experience and expertise. Many studies in ophthalmology are complex, and for this reason you need a team which understands the assessments and can focus on the details. KCAS Bio knows how to provide high quality data for your ophthalmology drug development project.
Ophthalmology treatment research, by leading scientists
There are a couple major challenges typically associated with ophthalmology as it relates to bioanalysis, one of the main being limited access to fluids or tissues from a living eye. It is difficult to develop highly sensitive methods when you can’t use a lot of the matrix available. At KCAS Bio, we have a rich history of conducting studies on eye tissues and using unique techniques that make a little sample go a long way in our processes. We have leveraged our rich history of knowing how to build a sensitive method with a minimal amount of volume. Additionally, our pharma team has become well-known for their PK analysis of small molecules, which makes us a perfect candidate for ophthalmological studies, as typically the treatment of the eye is a small molecule.
We employ rigorous quality practices that go beyond our competition. Processes are continuously improved to ensure we consistently deliver a complete outsourcing experience to clients.
KCAS Bio provides high quality science and data services that have benefits for the entire drug development journey.
Agile, responsive, and easy to work with
We prepare and adapt our ophthalmology research based on a deep understanding of your drug development ambitions and wider business objectives.
KCAS Bio scientific insights
Originally developed to monitor B cells producing antigen- or pathogen-specific antibodies, the ELISpot assay is widely used for evaluating vaccine-induced wanted immunogenicity. However, thanks to its high sensitivity, it is also a valuable tool for investigating unwanted immunogenicity, expanding its applications beyond traditional vaccine research. Early Applications in Preclinical…
Exploring cutting-edge methods for analyzing oligonucleotides in biological matrices. Oligonucleotide therapeutics have gained recent popularity given their vast applications in genetic disorders, cancers and infectious diseases. There are many challenges when developing bioanalytical methods for the quantitation of oligonucleotides, including stability, recovery, non-specific binding, chromatographic retention and ionization. In this…
Posters & Papers
This presentation, given at the 2025 AAPS PharmSci Conference by Dawn Dufield, PhD, Scientific Officer of Mass Spectrometry at KCAS Bio, reviews Bioanalytical Strategies for Therapeutic Drugs and Their Conjugates (ADCs, Oligos, siRNA, ASOs and AOCs/ARCs) by QqQ/HRMS. ADC_ARC Conjugates Presentation AAPS 2025_KCAS Bio…
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We've earned our reputation for delivering reliable, error-free data. We understand the importance of speed, flexibility, and consistency and only make promises we can keep.