
In today’s drug development efforts, Research and Development has increasingly expanded to include multi-country strategies. Over time, pharmaceutical and biotech companies have made substantial impact on economies where development work is conducted, and some countries have developed strategies (i.e. Australia) to attract this lucrative market via financial incentives and offering…

The world of medicine relies heavily on innovation, and Contract Research Organizations (CROs) are key players behind the scenes. But what exactly is a CRO, and why are these organizations so crucial to the development of new therapies and medical advancements? Let’s explore what CROs do and why they’re vital…

When it comes to flow cytometry instrumentation, there are a number of things that can be different. You may have different types of lasers, you might have a different path for the laser to follow to get to the detector, you can have different actual detectors, different filters in front…

Let’s face it – nobody likes batch effects (unless it has to do with cookies, but that’s for another podcast). In episode #9 of “The Conversational Flow”, Brian and Adam talk about Batch Effects which is when you’re having changes in the study that are not necessarily related to the…

For episode #8 of “The Conversational Flow” podcast, Brian and Adam spend the time discussing Receptor Occupancy Testing in Clinical Trials. Receptor occupancy (RO) assays are important in clinical trials because they provide valuable information about a drug’s binding characteristics and mechanism of action. Our hosts begin by outlining the…

For episode #7 of “The Conversational Flow”, Brian and Adam invite David Ambrose to join them as they continue their conversation about Receptor Occupancy assays. There are so many unique considerations around an RO assay and with any flow cytometry assay, the precision of that assay is important. Our hosts…

CEO of KCAS Bio, John Bucksath, joins Dom and John for a special 75th episode of “The Weekly Bioanalysis” podcast, and he is absolutely delighted to use the special episode to talk about the recent rebrand of KCAS to KCAS Bio! Mr Bucksath and our hosts discuss the reason the…

The newest episode of “The Conversational Flow” has Brian and Adam talking about the concepts around Receptor Occupancy and all the deceptively simple questions people often have about them, as well as the important but sometimes difficult answers to those questions. They talk about the biology of receptors and the…

During this newest episode of “The Conversational Flow”, Brian and Adam discuss cell sorting and the pivotal role it plays in molecular biology applications – enabling researchers to isolate specific cell populations from complex mixtures, as well as a number of other benefits. Our hosts dive into the importance of…

In our daily life we interact with many different people who help us by applying their expertise to deliver things we would otherwise struggle with. Often the differentiator for us, as consumers, is how we feel we’ve been treated by the people who are working on our behalf. The first…

As a Senior Director for Discovery in the pharma division at KCAS, I would like people to think of “Bioanalytical Discovery” as a stage in drug development; one where you are doing your final…

When I’m asked about the best way to go about selecting a CRO, my mind goes back to my second day at Magellan Laboratories in 1999 when I started my career years ago in this business. I had a customer who told me what it would take to be a…