Soluble Biomarker Analysis Services
For soluble biomarkers, we bring diverse analytical and molecular services together under one roof - combining immunoassays, multiplex platforms, and mass spectrometry - to deliver robust data that drive confident development decisions.
What are soluble biomarkers?
Biomarkers can be categorized as either soluble or cellular.
Soluble biomarkers are molecules found in body fluids such as blood, urine, cerebrospinal fluid, or saliva. These biomarkers include proteins and peptides (such as cytokines and hormones), metabolites, nucleic acids (like cell-free DNA and microRNAs), and autoantibodies. They are commonly measured using high-throughput analytical techniques such as mass spectrometry, multiplex immunoassays or molecular biology services.
What is the soluble biomarker strategy?
Sample Matrix
Plasma, serum, CSF, urine, etc.
Assay Development Time
Moderate; multiplexing possible
Quantitation
Quantitative (with standards/controls)
Regulatory Path
Well-established for LBA and LC/MS-MS
Challenges
Matrix effects, cross-reactivity, low abundance
Validation Parameters
Accuracy, precision, LLOQ, selectivity, stability
Technology and instrumentation for soluble biomarkers analysis
We offer one of the most comprehensive technology platforms for soluble biomarker testing, spanning LBA, hybrid LC-MS/MS and molecular services.
Additional resources
Blogs
In the ever-evolving landscape of drug development, biomarkers have emerged as critical tools for the mechanism of action, early proof of mechanism, safety, predictive, efficacy, and monitoring treatment response. As the field advances, two major classes of biomarkers have come to the forefront: soluble biomarkers and cellular biomarkers. While…
Blogs
Remember that childhood excitement the night before Christmas? Too excited to sleep, knowing something you wished for was finally within reach? That’s exactly the spirit fueling our teams in Lyon as we approach the end of June. We’re eagerly awaiting the arrival of a powerful new platform at our…
Blogs
Biomarkers (BMKs) have become fundamental tools in drug development, accelerating and optimizing targeted therapeutic innovation. As a bioanalytical CRO with over 15 years of experience in biomarker analysis, we’ve seen firsthand how the strategic integration of biomarkers can accelerate drug programs, help meet evolving regulatory standards,…
Tell us how we can help with your project
We've earned our reputation for delivering reliable, error-free data. We understand the importance of speed, flexibility, and consistency and only make promises we can keep.