Posts by Dawn Dufield, Ph.D.
Dawn R. Dufield, PhD is the Scientific Officer for Mass Spectrometry at KCAS Bio, where she has worked since 2018. Previously, she spent over 20 years at Pfizer specializing in quantitative large- and small-molecule LC-MS/MS. She was an early pioneer in combining immunoaffinity with LC-MS/MS for enhanced selectivity, now known as Hybrid LCMS, and co-authored a key white paper on validation of LCMS bioanalytical methods for protein biotherapeutics. Dawn has over 15 years of experience in ADC bioanalysis and recent focus on oligonucleotides/ARCs, with numerous publications and active involvement in WRIB, AAPS, and ASMS.
webinars
Originally produced by Xtalks on Friday, April 22, 2022 | 12pm EDT (NA) / 5pm BST (UK) / 6pm CEST (EU-Central) 60 min Webinar Description: Due to the relative maturity of the technology, most people’s instinct when thinking about bioanalysis of large molecules is towards ligand binding assays.
Blogs
Due to the relative maturity of the technology, most people’s instinct when thinking about bioanalysis of large molecules is towards ligand binding assays. However, we urge people to be open to a more flexible approach. Using hybrid LC-MS/MS can be an equally useful tool for quantitation of biological therapeutics and…
Blogs
There has been an increasing focus on large molecule therapeutics and pharmaceutical companies have increasingly aligned their development pipelines in that direction. This has resulted in more biological therapeutics coming to market. Last year,…
Blogs
Biomarkers are key drivers in the drug development process. Frequently, developing a panel of biomarkers to test a particular mechanism or hypothesis is critical to the success of a drug. At KCAS, we develop assays for custom panels or individual biomarkers based on client needs and can also assist with…
Blogs
Biomarker are key drivers in the drug development process. Frequently, developing a panel of biomarkers to test a particular mechanism or hypothesis is critical to the success of a drug. At KCAS, we develop assays for custom panels or individual biomarkers based on client needs and can also assist with…