Join us Tuesday November 10, 2020 at 11am EST| 8am PST| 4pm CET| 5pm CET

Bioanalytical liquid chromatography­–mass spectrometry (LC–MS) for small molecules is often referred to as a routine technology. That perception may be true for many drugs, but as pharmaceutical companies move into new areas, more  projects may present challenges in at least part of their scope, such as drug moiety, the matrices being assessed, the need for biomarker assessment, or high sensitivity requirements.

The challenge for bioanalytical service providers is to develop LC-MS assays to address these challenges and provide resulting methods that are robust and reliable enough to allow hand off to additional teams to support extensive sample analysis.

Key Learning Objectives:

  • Develop knowledge of the factors that present analytical challenges when developing bioanalytical methodologies
  • Gain insight into strategies for dealing with challenging analytes, matrices, and assay limitations
  • Review case studies presenting experiences with solving challenging LC-MS/MS assays and translating the solution to a production environment

Who Should Attend:

  • Directors, managers, and CEOs at pharma and biopharma companies


John Perkins, PhD, Senior Scientific Officer

John R. Perkins is the senior scientific advisor with a focus on LC/MS technologies at KCAS. Previously, he was at Q2Solutions and legacy companies for over 24 years working in quantitative LC/MS, principally with small molecules. His primary focus was on validation and sample analysis processes as well as managing customer relationships in Ithaca, NY. More recently he was responsible for the bioanalytical lab in Oss, The Netherlands.

John received his doctorate in supercritical fluid chromatography/mass spectrometry from University of Wales, College of Cardiff, UK. He did postdoctoral research on nanoscale separation techniques with mass spectrometry at NIEHS in Research Triangle Park. He earned a bachelor’s degree in chemistry from University of Reading, UK and a Master’s degree in advanced analytical chemistry from University of Bristol, UK

If you have any questions, please use the form below. Additionally, you can reach out to me directly, or any other member of KCAS’ leadership team. Thank you.