KCAS-podcast-thumb_TCF-019 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #19: “Building on Backbone Panels: Standardization, Speed, and Integration”

In the 19th episode of “The Conversational Flow”, our hosts, Brian and Adam, dive into the utility and innovation behind backbone panels in spectral flow cytometry, spotlighting a recent paper from BMS that presents a robust, flexible assay designed for immune monitoring using the Aurora platform. They discuss how backbone…

SpectralFlowCytometryPanel_KCASBio Posters & Papers
Read article Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational & Clinical Applications

Discover in this poster presented by David Ambrose at WRIB 2025, our work on the Global Harmonization of a Validated 15-Color Pan-Leukocyte Spectral Flow Cytometry Panel for Human Whole Blood in Support of Translational and Clinical Applications. Spectral Flow Cytometry Panel | KCAS Bio…

Driving Innovation Globally with Multisite Spectral Flow Cytometry Blogs
Read article Driving Innovation Globally with Multisite Spectral Flow Cytometry: Global Implementation of a Validated Flow Cytometry Panel

Modern immunology research requires high-complexity panels available wherever the patients are located. Deploying advanced flow cytometry instruments and panels across multiple global sites is therefore a transformative step in harmonizing immunological research and clinical trials. KCAS Bio has worked closely with Cytek to make this a reality by validating the…

KCAS-podcast-thumb_TCF-018 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #18: “Flow Cytometry & Cell Therapy: One Cell Can Make a World of Difference”

In this engaging episode of the podcast, hosts Brian Wile and Adam Cotty welcome special guests Michael Naso, Hillary Quinn, and Barry Morse from The Therapeutic Innovations Group—a powerhouse team of scientists and biotech veterans with decades of experience across biologics, small molecules, and cell therapy. The conversation dives deep…

T cells in Autoimmunity Blogs
Read article Driving Precision Insights with Spectral Flow Cytometry: a Focus on T Cells (Part 2)

Cell-based immunotherapies like Chimeric Antigen Receptor (CAR)-T cell therapy have been transforming the treatment of hematologic malignancies for more than a decade. Several groundbreaking studies (1) have led to a growing interest in applying these cell-based therapies to other T and B cell-mediated diseases.  One emerging application of CARs is…

KCAS-podcast-thumb_TCF-017 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #17: “Flow Validations and Guidance Document Changes in 2024-2025”

Episode 17 of The Conversational Flow podcast, hosted by Brian Wile and Adam Cotty, dives into the evolving landscape of flow cytometry networking and regulatory guidance, where they analyze recent FDA biomarker validation guidance, comparing it to existing industry standards like CLSI H62. Our hosts explore the challenges of harmonizing flow cytometry…

KCAS-podcast-thumb_TCF-016 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #16: “The Role of Flow in Drug Autoimmune Indication Research”

In episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology…

KCAS-podcast-thumb_TCF-015 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #15: “Fantastic Fluorophores and Where to Find Them (w/ Kelly Lundsten)”

In this exciting 15th episode of The Conversational Flow podcast, titled “Fantastic Fluorophores and Where to Find Them,” hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as…

Bioanalysis-zone-spotlight-3 Posters & Papers
Read article Evolving Best Practices in Flow Cytometry to Support Biomarker Analysis in Drug Development

This infographic explores the key trends in flow cytometry, software and instrumentation based on results from a recent Spotlight survey. It highlights the top challenges for biomarker analysis using flow cytometry, including lack of standardized control materials, sourcing a suitable laboratory and uncertain regulatory expectation, as well as what the…

CYTEK_ValidatedPanels_EBF2024_20241118 Posters & Papers
Read article Validation of a 15-Color Spectral Flow Cytometry Panel for Globally Harmonized Comprehensive Leukocyte Profiling in Human Whole Blood

Please download this poster, “Validation of a 15-Color Spectral Flow Cytometry Panel for Globally Harmonized Comprehensive Leukocyte Profiling in Human Whole Blood: Translational and Clinical Applications “ CYTEK_ValidatedPanels_EBF2024_20241118Download…

KCAS-podcast-thumb_TCF-014 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #14: “Modifying Flow Cytometry Panels: the “Backbone” of Flow Cytometry”

A flow cytometry backbone panel is a set of antibodies that can be used as a starting point for identifying cell types, and then supplemented with additional markers. On the most recent episode of “The Conversational Flow”, our hosts, Brian and Adam, spend some time together as they answer the questions…

KCAS-podcast-thumb_TCF-013 Podcasts
Listen to podcast Podcast (The Conversational Flow) Eps #13: “Low Content Analysis: When a smaller panel is better than a larger one”

During the most recent episode of “The Conversational Flow” podcast, our hosts Brian and Adam talk about those times when a smaller panel might be desirable over a larger panel. To dive deep into this discussion and really analyze all the angles of these questions, the guys have invited a…