Other (Mixed-Mode Macro-Molecules) Solutions
The type of services and assays with which KCAS has a lot of experience address a wide range of drug types and molecules. One example is mixed-mode macromolecules. This is where you take combined molecules from different classes of compounds and combine them, like a drug molecule with a synthetic polymer, or imbed it in a nanoparticle.
How can Mixed-Mode Macromolecules benefit your drug development project?
“Bioanalytical Discovery” is a stage in drug development where you are doing your final experiments and pilot studies before advancing to a GLP pre-clinical state. Taking advantage of mixed-mode macromolecules gives you as many options as possible to achieve your goals and get the data you need before making decisions that will be crucial to your project’s success.
KCAS Other Molecule Services
Antibody drug conjugates (ADCs) remain a popular oncology therapeutic modality. ADC analyses r…
The translation of an assay from Discovery to Preclinical/Clinical is an important part of dru…
Methods transferred into a new laboratory need to be re-established for regulatory compliance….
Affinity capture elution (ACE) is a method used in detecting ADA to increase the assay drug to…
Alkaline Hematin Kits are not the ordinary run of the mill clinical supply kit. Collecting for…
Since 2006, the KCAS has provided analytical support to companies developing treatments for me…
The accelerated pace within industry for quick “go / no-go” decisions in drug development, nec…
KCAS provides dose form analysis (DFA) for clinical and non-clinical investigations, with a wi…
Hybrid LCMS is a technique which combines an enrichment step (typically an antibody enrichment…
Clinical Sample Kits at KCAS are more than just clinical supplies for the collection of PK sam…
At KCAS, methods are developed with a fit-for-purpose design in mind, based on our Client’s ne…
A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed t…
KCAS has extensive experience in validating methods in a wide range of bioanalytical platforms…
Multi-plex analysis of biomarkers is a powerful tool for screening of many analytes in a small…
Regulated clinical bioanalysis is a key focus at KCAS, supporting both human and animal health…
The discovery phase in drug development requires rapid and reliable data in making key decisio…
PD Analysis is the assistance with design, regulatory requirements and final data interpretati…
Biomarkers come in many favors. They can vary from serum/plasma analytes to the measurement of…
Pharmacokinetics (PK) is the determination of the extent of Absorption, Distribution, Metaboli…
KCAS’ Clinical Sample Kit (CSK) service provides clinical sample kits for all phases of clinic…
Polymeric conjugates are polymer backbones used as delivery systems for drugs conjugated to th…
The Laboratory Collection Manual provides biological sample collection, processing, storage an…
Biomarkers come in many flavors and can be used as alternatives for assessing the functionalit…
Pharmacological activity of a drug molecule is influenced by many factors. The way a molecule…
Tissue bioanalysis is an essential area in understanding the extent of drug distribution, meta…