Tissue bioanalysis is an essential area in understanding the extent of drug distribution, metabolism and the regulation of biomarkers. KCAS can develop and validated methods in a wide range of tissues.
The ability to accurately measure an analyte in a given tissue (or other biological matrices) can clearly differentiate laboratories. KCAS has developed assays for hundreds of different matrices, including diverse tissues such as ophthalmic, pulmonary, CNS, sputum, bone, hair and tumor.
Having vast experience in how to process, stabilize and quantitate drugs and biomarkers in complex tissues, clearly is an area KCAS excels in. We have vast experience in homogenizing in a wide range of tissues and the appropriate constraints to improve analyte stability during processing of samples.
COMPOUND CLASSES
- Small Molecules
- Metabolites
- ADCs (Free and Total)
- Biomarkers
- Endogenous Molecules
- Peptides
- Lipids
- Metals
- ADCs (Mab, ADA)
- Amino Acids
- Cell Surface Receptors
- Fusion Proteins
- Glycosphingolipids
- Large Molecules (NBEs)
- Monoclonal Antibodies (mAbs)
- Multi-Valent Antibodies
- Novel Frameworks
- Oligonucleotides
- PEGylated Proteins
- Proteins
- RNA / DNA
- Signaling Pathways