Method Qualification
A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed to achieve not only a client’s objectives but budgetary constraints.
Method Qualifications are structure in three distinct levels. Level 1 has a discovery or proof-of-concept focus, using an abbreviated design. Level 2 employs matrix matched system calibration and Quality Controls, along with expanded stability assessment. Level 3 further establishes the method with additional parameter evaluation and tighter assay criteria.
These three research-grade levels are purposely designed by KCAS to provide rapid and reliable data at competitive pricing to our sponsors.
COMPOUND CLASSES
- Small Molecules
- Biomarkers
- Endogenous Molecules
- Peptides
- Lipids
- ADCs (Free and Total)
- ADCs (Mab, ADA)
- Amino Acids
- Cell Surface Receptors
- Fusion Proteins
- Glycosphingolipids
- Large Molecules (NBEs)
- Metabolites
- Metals
- Monoclonal Antibodies (mAbs)
- Multi-Valent Antibodies
- Novel Frameworks
- Oligonucleotides
- PEGylated Proteins
- Proteins
- RNA / DNA
- Signaling Pathways
RELATED ASSAYS
- Granisetron
- Cromolyn
- Cromolyn
- TBNK (CD16, CD56, CD19, CD25, CD14, CD4, CD8, CD3, HLA-DR, CD45)
- T subsets (CD45RA, CD197/CCR7, CD28, CD279/PD1, CD27, CD4, CD8, CD3, CD57, CD45)
- T reg intranuclear (CD45RA, CD25, CD39, CD4, FoxP3, CD3, Helios, CD45)
- TCR (TCR gamma-delta, TCR alpha-beta, HLA-DR, TCR Vdelta1, CD4, CD8, CD3, TCR Vdelta2, CD45)
- B cells (IgD, CD21, CD19, CD27, CD24, CD38, IgM, CD45)
- DCs (CD16, LINEAGE, CD1c, CD11c, Clee9A, CD123, HLA-DR, CD45)
- Intracellular (IFN gamma, TNF alpha, IL-2, CD8, CD3, CD4)
- DTC panel 1 (CD16, CD56, CD19, CD25, CD39, CD14, CD4, CD8, CD3, HLA-A2, CD45)
- DTC panel 2 (CD47, CD133, CD326, 7AAD, CD324, CD274, CD44, HLA-A2, CD45)
- ALL (CD7, CD79b, CD117, CD19, CD10, CD4, CD8, CD3, CD5, CD45)
- CLL (KAPPA, LAMBDA, CD117, CD19, CD10, CD20, CD23, CD43, CD5, CD45)
- MM1 (KAPPA, LAMBDA, CD48, CD56, CD117, CD138, CD38, CD33, CD19, CD45)
- MM2 (CD9, CD13, CD10, CD3, CD117, CD138, CD38, CD33, CD19, CD45)
- Histone DeAc (fixable L/D, H3 K27Ac, CD19, CD56, CD114, CD4, CD8, CD3, HLA-DR,DP,DQ, CD45)