Amino acids (21 naturally occurring) are valuable biomarkers for a variety of disorders and for monitoring effects of nutraceuticals. The assay separates and detects amino acids in plasma or other biological matrices through derivatization and UPLC-MS/MS. AccQ-Tag derivitaization chemistry increases sensitivity and chromatographic properties.
KCAS has developed a multiplexed panel of 21 naturally occurring amino acids. The method utilizes a simple derivatization procedure and UPLC-MS/MS giving excellent sensitivity and peak shape in a 7 minute method. This panel can be customized to the number amino acids as needed for your program. This assay is available for execution as a regulated or non-regulated method.
KCAS has already established this method which can be used off the shelf in both a non-regulated and regulated format. We can customize the panels as needed and potentially extend this to amino acid content in hydrolyzed proteins or peptides