Monoclonal Antibodies (mAbs)
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). Bispecific monoclonal antibodies can be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.
Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology, and medicine.
SERVICES
- Antibody Drug Conjugate (ADC) Analysis
- Aggregate Analysis
- Critical Reagent Characterization
- Pharmacodynamic (PD) Analysis
- Affinity Capture Elution (ACE) – Bridge Assay
- Cell Based Neutralizing Antibodies (Nabs)
- Fluorescence Testing
- Hybrid LC-MS/MS (Immunoaffinity LC-MS/MS)
- Immunogenicity Analysis
- Luminescence Testing
- Non-Clinical Non-GLP Sample Analysis
- Time Resolved Fluorescence
- Cell Culture Services
- Critical Reagents
- Method Transfer
- Method Development
- Method Qualification
- Method Validation
- Neutralizing Antibody (NAB) Studies
- Non-Clinical GLP Sample Analysis
- Pharmacodynamic (PD) Biomarkers
- Pharmacokinetic / Toxicokinetic (PK/TK) Analysis
- Polymeric Conjugate Testing
- Tissue Bioanalysis
- Multi-Plex Analysis
- Cell Sorting Services
- Cellular Phosphoflow Services
- Affinity Capture Elution (ACE) – Bridge Assay
- Molecular Services