Posts by Cassie Manning
Cassie Manning is a Principal Scientist in Mass Spectrometry Bioanalysis – Production at KCAS Bio, where she leads the execution and strategic direction of complex bioanalytical programs across the GLP environment. With extensive experience in method development, validation, and study oversight, she serves as a subject matter expert in mass spectrometry–based bioanalysis, supporting a wide range of assay types including tissue, biomarker, and enzymatic applications. Cassie provides scientific and operational leadership across multiple concurrent studies, ensuring high-quality, regulatory-compliant delivery while mentoring and developing scientific staff. She is recognized for her ability to resolve complex analytical challenges, optimize workflows, and drive efficiency, contributing to the successful advancement of drug development programs and strengthening KCAS Bio’s technical capabilities in bioanalysis.
Blogs
Oligonucleotide therapeutics have recently gained popularity as noted by recent increases in regulatory approvals of oligonucleotides as drugs, novel liquid nanoparticle delivery approaches, and on-target specificity. In the development of bioanalytical assays, there are many challenging aspects to consider when quantitating oligonucleotides, such as non-specific binding, stability, efficient ionization,…