Blogs
When you examine how to develop and validate/qualify a Biodistribution assay by PCR…
Blogs
Cell and Gene Therapies (CGTs) are types of treatment that uses cellular or genetic material with the goal of treating a disease or a disordered. Often it can be a combination of cell and gene therapies, which is the case for Chimeric antigen receptor T cells (CAR T-Cells). There are…
Blogs
Immunogenicity refers to the ability of a substance, such as an antigen or a vaccine, to provoke an immune response in an organism. The recognition of the substance as foreign triggers an immune response, which involves the production of antibodies and the activation of immune cells to fight against or…
Webinars
Produced by Bioanalysis Zone Recorded on December 11, 2023 Webinar available here. Webinar Description: In this webinar, Dominic Warrino discusses the bioanalytical considerations of immunogenicity of cell and gene therapies. Bioanalysis method development and method validation of immunogenicity assays for support of cell and…
Blogs
ELISpot (Enzyme-linked immunosorbent spot) is an immunoassay-based technique used to quantify cells that are capable of secreting proteins, including cytokines, cytotoxic molecules, and antibodies, when stimulated with the appropriate antigen. Initially designed to monitor the frequency of circulating antigen-specific memory B-cells, it is now commonly used to determine the frequency…
Blogs
Recently, Matthew Pennington, PhD (one of KCAS’s Senior Scientists) was the senior author on a publication entitled “A Validated Droplet Digital Polymerase Chain Reaction Assay for the Detection of Adeno Associated Viral Vectors in Bio Shedding Studies of Tears”. Below, Matt explains the significance in what they accomplished…
Podcasts
Special guest Carrie Vyhlidal, PhD of KCAS Bio joins John and Dom in the 68th episode of “The Weekly Bioanalysis” to discuss the ways molecular cell & gene therapy services has evolved and why their role will likely become more and more important to the world of bioanalytical…
Blogs
Biologics are drugs derived from complex molecules like antibodies. Over the last two decades they have re-emerged as…
Blogs
Being that it is a relatively “niche” segment of the industry, there are several key areas that need to be considered in the field of molecular services related to cell and gene therapies. First and foremost, it is important to recognize that regulatory guidelines within this field are…
Blogs
Cell and Gene Therapies (CGTs) has an estimated market size value in 2022 of USD 8.22 billion and a revenue forecast in 2030 of USD 24.5 billion. This is a CAGR (compound annual growth rate) of 14.6% from 2022 to 2030. Needless to say, the…
Blogs
With the extensive advances in technologies like CRISPR and CAR-T, cell and gene therapy has grown to become a viable way for treating Cancer as well as other diseases. Our team has over 100+ years of collective expertise in molecular services using qPCR and ddPCR for support of…