Pharmaceutical Services

.

Antibody drug conjugates (ADCs) remain a popular oncology therapeutic modality. ADC analyses require. . .

.

The translation of an assay from Discovery to Preclinical/Clinical is an important part of drug deve. . .

.

Methods transferred into a new laboratory need to be re-established for regulatory compliance.  The. . .

.

The analysis of free amino acids (20 naturally occurring) in plasma or other biological matrices thr. . .

.

Bioavailability (BA) is the percentage that a drug or its pro-drug form is absorbed into the general. . .

.

A significant number of drugs contain a chiral center that allows the compound to properly fit into. . .

.

Regulated clinical bioanalysis is a key focus at KCAS. Our data has been used in the approval of ove. . .

.

Critical reagents are essential components of analytical methods whose unique characteristics are cr. . .

.

The accelerated pace within industry for quick “go / no-go” decisions in drug development, necessita. . .

.

KCAS provides dose form analysis (DFA) for clinical and non-clinical investigations, with a wide ran. . .

.

At KCAS, methods are developed with a fit-for-purpose design in mind, based on our Client’s needs. T. . .

.

A fit-for-purpose approach is used by KCAS in method qualifications. Each method is designed to achi. . .

.

KCAS has extensive experience in validating methods in a wide range of bioanalytical platforms.  Our. . .

.

Regulated clinical bioanalysis is a key focus at KCAS, supporting both human and animal health progr. . .

.

The discovery phase in drug development requires rapid and reliable data in making key decisions for. . .

.

PD Analysis is the assistance with design, regulatory requirements and final data interpretation. Of. . .

.

Biomarkers come in many favors. They can vary from serum/plasma analytes to the measurement of drug. . .

.

Pharmacokinetics (PK) is the determination of the extent of Absorption, Distribution, Metabolism and. . .

.

Polymeric conjugates are polymer backbones used as delivery systems for drugs conjugated to them. Po. . .

.

The extent to which a drug binds to plasma proteins can range from neglible to 99.9+% with compounds. . .

.

Pharmacological activity of a drug molecule is influenced by many factors.  The way a molecule is me. . .

.

Tissue bioanalysis is an essential area in understanding the extent of drug distribution, metabolism. . .