KCAS has established a wide range of assays in various biological matrices.
The methods tabulated below vary from Qualified to Fully Validated Methods.

Ibuprofen

Matrix: Human Plasma
LLOQ: 25
Unit: ng/mL

Platform: LC-MS/MS

Imipramine / Desipramine

Matrix: Human Plasma
LLOQ: 0.1
Unit: ng/mL

Platform: LC-MS/MS

Indomethacin

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Isotretinoin / 4-Oxo-Isotretinoin

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Isradapine

Matrix: Human Plasma
LLOQ: 100
Unit: pg/mL

Platform: LC-MS/MS

Ketoconazole / Clotrimazole

Matrix: Human Plasma
LLOQ: 50 / 5
Unit: ng/mL

Platform: LC-MS/MS

Ketoprofen

Matrix: Human Plasma
LLOQ: 1
Unit: ng/mL

Platform: LC-MS/MS

Levofloxacin

Matrix: Rabbit Plasma
LLOQ: 0.2
Unit: mcg/mL

Platform: LC-MS/MS

Lidocaine

Matrix: Dog Plasma
LLOQ: 0.1
Unit: ng/mL

Platform: LC-MS/MS

Lidocaine

Matrix: Dog Urine
LLOQ: 0.1
Unit: ng/mL

Platform: LC-MS/MS

Lidocaine

Matrix: Dog Tissue
LLOQ: 10
Unit: ng/g

Platform: LC-MS/MS

Lidocaine

Matrix: Rat Plasma
LLOQ: 0.5
Unit: ng/mL

Platform: LC-MS/MS

Lorazepam

Matrix: Human Plasma
LLOQ: 1
Unit: ng/mL

Platform: LC-MS/MS

Losartan / Carboxylosartan

Matrix: Human Plasma
LLOQ: 2 / 2
Unit: ng/mL

Platform: LC-MS/MS

Meloxicam

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Memantine

Matrix: Human Plasma
LLOQ: 0.5
Unit: ng/mL

Platform: LC-MS/MS

Memantine N-Glucuronide

Matrix: Human Plasma
LLOQ: 0.2
Unit: ng/mL

Platform: LC-MS/MS

Mephenytoin, (R)- / Mephenytoin, (S)-

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Mephenytoin, (R)- / Mephenytoin, (S)-

Matrix: Human Saliva
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Mephenytoin, (R)- / Mephenytoin, (S)-

Matrix: Human Urine
LLOQ: 0.1
Unit: mcg/mL

Platform: LC-MS/MS

Mephenytoin, (R)- / Mephenytoin, (S)-

Matrix: Human Urine
LLOQ: 0.1
Unit: mcg/mL

Platform: LC-MS/MS

Mercaptopurine, 6- / 6-Thiouric Acid

Matrix: Human Plasma
LLOQ: 2 / 20
Unit: ng/mL

Platform: LC-MS/MS

Mercaptopurine, 6- / 6-Thiouric Acid

Matrix: Human Urine
LLOQ: 6 / 60
Unit: ng/mL

Platform: LC-MS/MS

Metformin

Matrix: Human Plasma
LLOQ: 20
Unit: ng/mL

Platform: LC-MS/MS

Methylnicotinamide

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Methylnicotinamide

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Methylphenidate

Matrix: Human Plasma
LLOQ: 100
Unit: pg/ml

Platform: LC-MS/MS

Methylprednisolone

Matrix: Human Plasma
LLOQ: 2.5
Unit: ng/mL

Platform: LC-MS/MS

Metoprolol

Matrix: Human Plasma
LLOQ: 1
Unit: ng/mL

Platform: LC-MS/MS

Midazolam / 1-Hydroxymidazolam / 4-Hydroxymidazolam

Matrix: Human Urine
LLOQ: 10 / 2 / 2
Unit: ng/mL

Platform: LC-MS/MS

Midazolam / a-Hydroxymidazolam

Matrix: Human Urine
LLOQ: 20 / 0.5
Unit: ng/mL

Platform: LC-MS/MS

Molindone

Matrix: Human Plasma
LLOQ: 0.5
Unit: ng/mL

Platform: LC-MS/MS

Morphine / Morphine-3-Glucuronide / Morpine-6-Glucuronide

Matrix: Dog Plasma
LLOQ: 0.5 / 5 / 2
Unit: ng/mL

Platform: LC-MS/MS

Morphine / Morphine-3-Glucuronide / Morpine-6-Glucuronide

Matrix: Human Plasma
LLOQ: 0.5 / 5 / 2
Unit: ng/mL

Platform: LC-MS/MS

Morphine / Morphine-3-Glucuronide / Morpine-6-Glucuronide

Matrix: Ovine Plasma
LLOQ: 0.5 / 5 / 2
Unit: ng/mL

Platform: LC-MS/MS

Moxifloxacin

Matrix: Human DBS
LLOQ: 100
Unit: ng/mL

Platform: LC-MS/MS

Moxifloxacin

Matrix: Human Plasma
LLOQ: 20
Unit: ng/mL

Platform: LC-MS/MS

Niacin (Nicotinic Acid) / Nicotinuric Acid

Matrix: Human Urine
LLOQ: 25
Unit: ng/mL

Platform: LC-MS/MS

Nifedipine / NPO

Matrix: Human Plasma
LLOQ: 1
Unit: ng/mL

Platform: LC-MS/MS

Noroxycodone

Matrix: Human Plasma
LLOQ: 0.25
Unit: ng/mL

Platform: LC-MS/MS

Olanzapine

Matrix: Human Plasma
LLOQ: 0.1
Unit: ng/mL

Platform: LC-MS/MS

Omeprazole

Matrix: Human Plasma
LLOQ: 0.25
Unit: ng/mL

Platform: LC-MS/MS

Ondansetron

Matrix: Human Plasma
LLOQ: 0.5
Unit: ng/mL

Platform: LC-MS/MS

Oxandrolone

Matrix: Human Plasma
LLOQ: 0.25
Unit: ng/mL

Platform: LC-MS/MS

Oxybutynin / N-Desethyloxybutynin

Matrix: Human Plasma
LLOQ: 0.0500 / 0.25
Unit: ng/mL

Platform: LC-MS/MS

Oxycodone / Noroxycodcone / Oxymorphone

Matrix: Human Plasma
LLOQ: 0.25
Unit: ng/mL

Platform: LC-MS/MS

Oxymorphone

Matrix: Human Plasma
LLOQ: 0.25
Unit: ng/mL

Platform: LC-MS/MS

Paclitaxel

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

Paclitaxel

Matrix: Human Urine
LLOQ: 5
Unit: ng/mL

Platform: LC-MS/MS

Pantoprazole

Matrix: Human Plasma
LLOQ: 10
Unit: ng/mL

Platform: LC-MS/MS

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