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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css=".vc_custom_1544820034476{padding-top: 25px !important;padding-right: 15px !important;padding-bottom: 25px !important;padding-left: 25px !important;background-color: #ffffff !important;}" z_index=""][vc_column][vc_column_text]KCAS is the first GLP laboratory to qualify all 54 biomarkers offered as a V-Plex (Validated Plex) by MSD. The a la carte style allows for customization of panels that will...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css=".vc_custom_1544820034476{padding-top: 25px !important;padding-right: 15px !important;padding-bottom: 25px !important;padding-left: 25px !important;background-color: #ffffff !important;}" z_index=""][vc_column][vc_column_text]Several important classes of drugs are inherently unstable in biological fluids. Examples include alkylating agents, cytostatic nucleosides, drugs with ester, aldehyde, thiol, nitroxyl or lactone functional groups, and small molecule compounds...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css=".vc_custom_1550010268522{padding-top: 25px !important;padding-right: 15px !important;padding-bottom: 25px !important;padding-left: 25px !important;}" z_index=""][vc_column][vc_column_text] Want to meet our presenting author, a business development representative or a senior scientific officer? Send us a note to set up a meeting   Find KCAS We are located at booth 2424 marked by...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text] The 505(b)(2) drug development path, in contrast to traditional development of a new, never been approved drug (described under 505(b)(1) of the Federal Food, Drug, and Cosmetic Act) or ANDA (described under Section 505(j) of the Act) for a generic drug that is...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text] Tissue and tumor sample testing are valuable matrix to test for drug levels (PK) and biomarkers (PD). They are understudied in my opinion as far too many studies result in no data or uninterpretable data. The root cause is a break down in...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text] Designing a tissue assay in accordance to the FDA bioanalytical method validation (BMV) guidance involves three key questions. First, can control tissue be easily obtained in bulk quantities or should a surrogate tissue approach be considered? Second, what sample processing procedures should be...