Rosuvastatin in Human Plasma Assay

 

 

 

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: Potassium EDTA

Storage Temperature: -20 °C or -70 °C

LLOQ: 0.200 ng/mL

ULOQ: 76.8 ng/mL

Sample Volume: 250 mcL

Precision & Accuracy:

  • LLOQ QC: 4.4% CV; -6.7% Bias
  • Low QC: 4.0% CV; -2.1% Bias
  • Mid QC: 2.6% CV; 0.2% Bias
  • High QC: 2.3% CV; -0.7% Bias
  • Above Range QC (5x Dilution): 2.0% CV; -1.1% Bias

Stability:

  • Short-Term (Bench-Top): 30 hours and 42 minutes
  • Long-Term: 75 days at -20 °C; 75 days at -70 °C
  • Freeze/Thaw Cycles: 4

Method Number: V2334P1