Paroxetine in Human Plasma Assay

 

 

 

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: Potassium EDTA

Storage Temperature: -20 °C or -70 °C

LLOQ: 0.200 ng/mL

ULOQ: 100 ng/mL

Sample Volume: 250 mcL

Precision & Accuracy:

  • LLOQ QC: 8.1% CV; -12.0% Bias
  • Low QC: 5.8% CV; -4.1% Bias
  • Mid QC: 7.3% CV; -2.6% Bias
  • High QC: 3.0% CV; -0.5% Bias
  • Above Range QC (5x Dilution): 4.0% CV; -0.8% Bias

Stability:

  • Short-Term (Bench-Top): 4 hours and 23 minutes
  • Long-Term: 55 days at -20 °C and 18 weeks at -70 °C
  • Freeze/Thaw Cycles: 3

Method Number: V2255P1