Memantine in Human Plasma Assay

 

 

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: Potassium EDTA

Storage Temperature: -20 °C

LLOQ: 0.500 ng/mL

ULOQ: 48.0 ng/mL

Sample Volume: 100 mcL

Precision & Accuracy:

  • LLOQ QC: 7.8% CV; -1.5% Bias
  • Low QC: 3.3% CV; 4.6% Bias
  • Mid QC: 2.1% CV; -3.0% Bias
  • High QC: 4.0% CV; 3.2% Bias
  • Above Range QC (5x Dilution): 2.1% CV; 11.3% Bias

Stability:

  • Short-Term (Bench-Top): 22 hours and 36 minutes
  • Long-Term: 46 days at -20 °C
  • Freeze/Thaw Cycles: 4

Method Number: V2337P1