Carisbamate in Human Plasma

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: Sodium Heparin

Storage Temperature: -20 °C

LLOQ: 5 ng/mL

ULOQ: 1000 ng/mL

Sample Volume: 500 mcL

Precision & Accuracy:

  • LLOQ QC: 7.8% CV; 10.6% Bias
  • Low QC: 8.5% CV; -2.2% Bias
  • Mid QC: 5.6% CV; -7.3% Bias
  • High QC: 6.5% CV; -6.2% Bias
  • Above Range QC (5x Dilution): 2.9% CV; -9.0% Bias

Stability:

  • Short-Term (Bench-Top): 4 hours
  • Long-Term: 180 days at both -20 °C and -70 °C
  • Freeze/Thaw Cycles: 3

Method Number(s): V1432P1 / S1432P1