Captisol Human Plasma Assay Performance

 

 

 

 

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: K2EDTA

Storage Temperature: -20 °C and -70 °C

LLOQ: 5 mcg/mL

ULOQ: 960 mcg/mL

Sample Volume: 100 mcL

Precision & Accuracy:

  • LLOQ QC: 5.0% CV; -7.2% Bias
  • Low QC: 3.3% CV; 3.1% Bias
  • Mid QC: 1.3% CV; 2.7% Bias
  • High QC: 2.1% CV; -5.3% Bias
  • Above Range QC (5x Dilution): 1.2% CV; -3.0% Bias

Stability:

  • Short-Term (Bench-Top): 17 hours
  • Long-Term: 34 days at -20 °C and -70 °C
  • Freeze/Thaw Cycles: 4

Method Number: V2370P1