Atomoxetine Human Plasma Assay Performance

 

 

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: Potassium EDTA

Storage Temperature: -20 °C or -70 °C

LLOQ: 10 ng/mL

ULOQ: 960 ng/mL

Sample Volume: 100 mcL

Precision & Accuracy:

  • LLOQ QC: 8.3% CV; -0.1% Bias
  • Low QC: 3.5% CV; -0.1% Bias
  • Mid QC: 1.5% CV; 0.6% Bias
  • High QC: 2.1% CV; 1.4% Bias
  • Above Range QC (5x Dilution): 3.1% CV; 1.3% Bias

Stability:

  • Short-Term (Bench-Top): 22 hours and 25 minutes
  • Long-Term: 56 days at -20 °C
  • Freeze/Thaw Cycles: 4

Method Number: V2329P1