N-Desmethyl Terbinafine Compound

 

 

 

 

 

Method: LC-MS/MS

Matrix: Human Plasma

Anticoagulant: Potassium EDTA

Storage Temperature:  -70 °C

LLOQ: 40 pg/mL

ULOQ: 10,200 pg/mL

Sample Volume: 150 mcL

Precision and Accuracy:

  • LLOQ QC: 10.5 % CV; -5.1 % Bias
  • Low QC: 6.7 % CV; -2.2 % Bias
  • Mid QC: 3.3 % CV; 0.9 % Bias
  • High QC: 2.9 % CV; 1.2 % Bias
  • Above Range QC (5x Dilution): 1.8 % CV; -0.6% Bias

Stability:

  • Short-Term (Bench-Top): 23 hrs and 54 min
  • Long-Term: 477 days at -70 °C
  • Freeze/Thaw Cycles: 4

Comments: Assay Quantitates Terbinafine (40 – 10,200 pg/mL).

Method Number: VTALI7902P1